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When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines. It was unclear, however, what exactly was causing this reaction. In a new study, Yale scientists have identified the immune signature of these heart inflammation cases. These findings, published May 5 in the journal Science Immunology, rule out some of the theorized causes of the heart inflammation and suggest potential ways to further reduce the incidence of a still rare side effect of vaccination, the authors say.

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Carrie Lucas , Jon Klein , Akiko Iwasaki , Anis Barmada , Yale School Of Medicine , Centers For Disease , New Haven , Science Immunology , Disease Control , Sterling Professor , Inci Yildirim , Yale School ,

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