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Individual receptors caught in the act of coupling

 E-Mail NEW YORK, NY A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children s Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.  The researchers used the technique to zoom in on individual receptor proteins on the surface of living cells to determine if the receptors work solo or come together to work as pairs. This work appeared in the April issue of  Nature Methods. If two different receptors come together to form a dimer with distinctive function and pharmacology, this might allow for a new generation of drugs with greater specificity and reduced side effects, says Jonathan Javitch, MD, PhD, the Lieber Professor of Experimental Therapeutics in Psychiatry at VP&S.  

Individual Receptors Caught in Act of Coupling

Columbia University Irving Medical Center A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children’s Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs. The researchers used the technique to zoom in on individual receptor proteins on the surface of living cells to determine if the receptors work solo or come together to work as pairs. This work appeared in the April issue of Nature Methods. “If two different receptors come together to form a dimer with distinctive function and pharmacology, this might allow for a new generation of drugs with greater specificity and reduced side effects.”

Yes, vaccines block most transmission of COVID-19

Yes, vaccines block most transmission of COVID-19
nationalgeographic.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nationalgeographic.com Daily Mail and Mail on Sunday newspapers.

The New Normal: After being vaccinated, what can you do to decrease your chances of getting sick?

The New Normal: After being vaccinated, what can you do to decrease your chances of getting sick? News 12 Staff Updated on:Apr 19, 2021, 9:47am EDT News 12 s Elizabeth Hashagen was joined by Dr. Thomas McGinn this morning to discuss the Johnson & Johnson vaccine pause and virus variants. A decision about whether to resume administering the Johnson & Johnson COVID-19 vaccine should come this Friday. The two most likely options are restricting the shot to an age group, such as men and women over 50 years, or allowing a return to widespread use but with an added warning. While it s true that the virus variants are a significant public health concern, the unrelenting focus on each new variant has created undue alarm and a false impression that vaccines don t protect us against the various variants that continue to emerge.

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