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Potential Load-Bearing Implants Made of Additively Manufactured Ti-Ta-Cu Alloys

Traditional methods, such as topical or systemic antibiotic administration, may not be effective in preventing colonization, even though it is a major cause of failure and clinical complications for load-bearing metallic orthopedic implants. This is especially true in the case of secondary infection, which frequently necessitates surgical removal of the implants and, in extreme cases, even limb amputation.

3D-Printed, Infection-Resistant Metals for Implants Developed

Infection-resistant, 3D-printed metals developed for implants

A novel surgical implant developed by WSU researchers was able to kill 87% of the bacteria that cause staph infections in laboratory tests, while remaining strong and compatible with surrounding tissue like current implants.

Infection-resistant, 3D-printed metals develo

<p>A novel surgical implant was able to kill 87% of the bacteria that cause staph infections in laboratory tests, while remaining strong and compatible with surrounding tissue like current implants. The work could someday lead to better infection control in many common surgeries, such as hip and knee replacements, that are performed daily around the world.&nbsp; Bacterial colonization of the implants is one of the leading causes of their failure and bad outcomes after surgery.&nbsp;Using 3D-printing technology, the WSU researchers added 10% tantalum, a corrosion-resistant metal, and 3% copper to the titanium alloy typically used in implants. When bacteria come into contact with the material&rsquo;s copper surface, almost all of their cell walls rupture. Meanwhile, the tantalum encourages healthy cell growth with surrounding bone and tissue leading to expedited healing for the patient. The researchers spent three years on a comprehensive study of their implant, assessing its mechanical properties, biology and antibacterial response both in the lab and in animal models.They also studied its wear to make sure that metal ions from the implant won&rsquo;t wear off and move into nearby tissue causing toxicity.</p>

3D-printed metal implant kills bacteria to fight infection

Novel 3D-printed implant could revolutionize infection control in surgery

A novel surgical implant developed by Washington State University researchers was able to kill 87% of the bacteria that cause staph infections in laboratory tests, while remaining strong and compatible with surrounding tissue like current implants.

Infection-resistant, 3D-printed metals developed for implants

How to Combine Two Metals Into One Layer

A new combination of welding & computing allows for the creation of a bimetallic metal that's stronger than either of its individual steel materials.

Investigating the porous metals in orthopedic implants and beyond

It all adds up

Innovating in 3D printing at Washington State University