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New mechanism discovered: B cells' contribution to immune tolerance in thymus gland

Immune cells must learn not to attack the body itself. A team of researchers from the Technical University of Munich (TUM) and the Ludwig Maximilian University of Munich (LMU) has discovered a previously unknown mechanism behind this: other immune cells, the B cells, contribute to the "training" of the T cells in the thymus gland.

Munich
Bayern
Germany
Ludger-klein
Thomas-korn
Biomedical-center
Technical-university-of-munich
Ludwig-maximilian-university-of-munich
Technical-university
Ludwig-maximilian-university
Experimental-neuroimmunology
Principal-investigator

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis.

Fran-ferrer
Juan-francisco
Eduardo-rubio
Sant-crist
Research-group-in-neuromuscular-pathology
Biomedical-research-networking-center
Stopela-association
University-of-zaragoza-unizar
Stopela-patient-association
Tissue-engineering
Universitat-polit
Instituto-de-investigaci

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

Delindaa-johnson
Jeffreya-johnson
Jacob-rosaline-cohn
Nathan-gianneschi
Jeffrey-johnson
Johnson-lab
Weinberg-college-of-arts
Northwestern-university
Madison-school-of-pharmacy
International-institute-for-nanotechnology
University-of-wisconsin
Rosaline-cohn-professor

Researchers unveil improved method to study the brain

Scientists at the University of Pennsylvania unveil a revolutionary cryo-electron tomography method, offering unprecedented insights into brain structures.

Brain
Cryo-electron
Omography
Lzheimer-x27-s
Ultiple
Clerosis
Ellular-structures
Reezing
Lash-freezing
Issue
Utopsy

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

Heidelberg
Baden-wüberg
Germany
German
Hilmar-bading
Jing-yan
Department-of-neurobiology
Interdisciplinary-center
European-research-council
Heidelberg-university
German-research-foundation
Alexander-von-humboldt-foundation

World-first discovery offers potential cure for lupus

Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment.

Australia
Monash
South-australia
Australian
Australians
Rachel-cheong
Eric-morand
Peter-eggenhuizen
Vu-nguyen
Nature-communications
Lupus-research-alliance
Monash-university

Do lifestyle factors affect late-life cognition and dementia pathology impact?

Scientists from the Rush University Medical Center in Chicago, United States, investigated whether brain pathology related to dementia, such as cerebrovascular pathology, phosphorylated tau fibril tangles, and β-amyloid accumulation, modify the association between healthy lifestyle choices and cognition during the later years in life.

United-states
Chicago
Illinois
Rush-university-medical-center
Jacob-lund-shutterstock
Healthy-lifestyle
Older-adults-with-common-neuropathologies
Image-credit
Mediterranean-dietary-approaches
Stop-hypertension
Neurodegenerative-delay
Dementia

Study shows nuanced pregnancy outcomes for pregnant individuals with autoimmune disease

For many aspiring mothers with autoimmune disease, pregnancy can be daunting and full of unknowns. In some cases, those suffering from specific autoimmune conditions have chosen to forego pregnancy altogether due to concerns about their disease treatments and adverse pregnancy outcomes.

Philip-mease
Jennifer-hadlock
Clinical-health
Institute-for-systems-biology
Systems-biology
Professor-jennifer-hadlock
Autoimmune-disease
Regnancy
Rthritis
Nflammatory-bowel-disease
Upus
Esearch

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