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Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

A new study from scientists at La Jolla Institute for Immunology (LJI) gives researchers a guide to neutralizing Lassa virus using a trio of rare antibodies isolated from survivors of Lassa virus infection.

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Erica-ollmann-saphire
Luis-branco
Kathryn-hastie
Emily-henderson
Antibody-discovery-center
Saphire-lab
Tulane-university
Drug-administration
University-of-texas-medical-branch
Scripps-research
Zalgen-labs

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

A new study showed that SARS-CoV-2 Spike N-glycosylation patterns, intracellular lectins, and the associated molecular chaperones play crucial roles in the viral-host-cell invasion and function.

Science-advances
Spiken-glycosylation
Chaperones
Coronavirus-disease-covid-19
Glycans
Ars
Ars-cov-2
Ell
Oronavirus
Ovid-19
Glycan

Synthetic mucin gels against HIV-1 and HSV-2 transmission

In a new study, researchers assessed the effectiveness of synthetic mucin gels in the inhibition of human immunodeficiency virus-1 (HIV-1) and herpes simplex virus-2 (HSV-2) Transmission.

Healing-properties-augment-lubricity
Advanced-science
Synthetic-mucin-gels
Self-healing-properties-augment-lubricity
Image-credit
Hiv
Hiv-1
Aldehydes
Ell
Oronavirus
Efficacy

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

In a recent study posted to the bioRxiv preprint server, researchers from Spain, the United Kingdom, and the United States used chemical tools to uncover the molecular details of glycan-mediated modulation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) processing.

United-states
United-kingdom
Spain
Resonance-energy-transfer
O-linked-sialoglycans-modulate
Mutational-trajectory
Image-credit
Uten-hagen
I-tagged-modified-galn
Coronavirus-disease-covid-19
Ars

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