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Keytruda extends survival in high-risk triple negative breast cancer

A study assessing the efficacy of pembrolizumab met a key secondary endpoint of extending OS, in combination with chemotherapy, among patients with high-risk early-stage triple-negative breast cancer, according to the agent’s manufacturer. Pembrolizumab (Keytruda, Merck), an anti-PD-1 therapy, has two approved indications for triple-negative breast cancer.

Bereavement care, often an 'afterthought,' should be public health priority

Health care institutions and their staffs must take action to ensure bereavement care shifts from “an afterthought to a public health priority,” according to a position paper published in The Lancet Public Health.Bereavement support often is considered part of palliative care; however, there often is a lack of continuity of care for bereaved individuals after a person dies in

Type of menopausal hormone therapy may influence cancer risk

HPV vaccination linked to lower risk for related cancers among men

Most young women can conceive, give birth after breast cancer treatment

Many childhood cancer survivors do not undergo recommended tests for late effects

Most childhood cancer survivors are not up to date on guideline-recommended screening for late effects of cancer treatment or second malignancies, according to study results.The retrospective, population-based study — led by researchers at The Hospital for Sick Children and Women’s College Hospital in Toronto — included data from 3,241 adult survivors of childhood cancer. All

Despite enduring disparities, stem cell transplants expand across all races, ethnicities

The amount of autologous and allogeneic hematopoietic stem cell transplants for hematologic disorders has increased over time in tandem with longer survival, according to results of an observational study. Researchers observed improvements across all racial and ethnic groups but found that disparities related to treatment outcomes still exist.

Active cancer treatment linked to increased risk for sudden cardiac arrest

Active cancer treatment is associated with increased risk for sudden cardiac death, especially among patients younger than 74 years old and those with a history of heart failure, results from a retrospective study showed. The findings, published in The American Journal of Cardiology, indicated that patients who harbored multiple risk factors had a significantly higher probability of sudden

Racing modified cells against each other in humans may be the next step in gene therapies

The next evolution of gene therapies may involve pitting T cells with different modifications against one another in a “race” inside a human to determine which edits produce the best results against a tumor, an expert panel predicted. Researchers across the globe have discovered dozens of genes that could be targeted to make T cells more durable and effective in tumor

ASCO to recognize women in oncology with high honors

Several women oncologists will be honored during this year’s ASCO Annual Meeting.ASCO’s special awards recognize clinicians and scientists who have globally reshaped cancer care.