Mitochondrial DNA Dysfunction Points to Potential Therapeutic Targets against Inflammation genengnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from genengnews.com Daily Mail and Mail on Sunday newspapers.
Inflammation Linked to Faulty DNA Disposal System miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
<p>Salk scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.</p>
Cells in the human body contain power-generating mitochondria, each with their own mtDNA-;a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy.
Faulty DNA disposal system causes inflammation sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
Faulty DNA disposal system causes inflammatio eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Many scientists credit teenage jobs and university or summer side roles for imparting important transferable skills and valuable life experiences. Many scientists credit teenage jobs and university or summer side roles for imparting important transferable skills and valuable life experiences.
Cracking the case of mitochondrial repair and replacement in metabolic stress sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
Mitochondria power-supply failure may cause age-related cognitive impairment: Scientists find mitochondria at dysfunctional synapses fail to meet energetic demand, supplying either too much or too little power and potentially causing age-related cognitive impairment sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.