The Nigeria international made a key contribution in the encounter to help his side return to winning ways after losing against Osasuna in their last league game.
Villarreal dominated the first half of the game and came close to opening the scoring a number of times before eventually breaking the deadlock in the 36th minute.
Chukwueze found Alcacer with a fine pass and the forward controlled the ball before firing his effort into the back of the net, beyond the reach of goalkeeper Dominik Livakovic.
Moments before the half-time break, Moreno doubled the lead for the Yellow Submarine with a well-taken effort after pouncing on a loose ball.
A draw would be enough for the hosts and that is priced at
Villarreal vs Dinamo Zagreb Team News
Unai Emery is missing only Vicente Iborra and Pervis Estupinan, while the majority of his strongest XI should be raring to go after most were rested for the 2-1 defeat against Osasuna at the weekend.
Bruno Petkovic played only 30 minutes of the first leg and missed Dinamo’s win on Sunday, so is a doubt for this one.
Villarreal vs Dinamo Zagreb Preview
Villarreal dominated possession in the first leg but it was a game of few real chances, settled only by Moreno’s penalty following a handball by Kevin Theophile-Catherine.