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Immune-stimulating drug before surgery shows promise in early-stage pancreatic cancer

 E-Mail PHILADELPHIA Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center (ACC) at the University of Pennsylvania. Changing the microenvironment from so-called T cell poor to T cell rich with a CD40 agonist earlier could help slow eventual progression of the disease and prevent cancer from spreading in more patients. The data which included 16 patients treated with the CD40 agonist selicrelumab was presented today by Katelyn T. Byrne, PhD, an instructor of Medicine in the division of Hematology-Oncology in the Perelman School of Medicine at the University of Pennsylvania, during a plenary session at the American Association for Cancer Research annual meeting (Abstract #CT005).

You got vaccinated Now what? 7 things to know for your post-COVID vaccine behavior

You got vaccinated Now what? 7 things to know for your post-COVID vaccine behavior
msn.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from msn.com Daily Mail and Mail on Sunday newspapers.

COVID-19 origins still obscure, what are the next steps for WHO s experts?

COVID-19 origins still obscure, what are the next steps for WHO s experts? Firstpost 2 hours ago The New York Times © Provided by Firstpost COVID-19 origins still obscure, what are the next steps for WHO s experts? The joint international and Chinese mission organized by the World Health Organization on the origins of COVID released its report last week suggesting that for almost every topic it covered, more study was needed. What kind of study and who will do it is the question. The report suggested pursuing multiple lines of inquiry, focused on the likely origin of the coronavirus in bats. It concluded that the most likely route to humans was through an intermediate animal, perhaps at a wildlife farm. Among future efforts could be surveys of blood banks to look for cases that could have appeared before December 2019 and tracking down potential animal sources of the virus in wildlife farms, the team proposed.

The Vast Viral World: What We Know (and Don t Know) - Issue 99: Universality

The Vast Viral World: What We Know (and Don t Know) - Issue 99: Universality
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With virus origins still obscure, WHO and critics look to next steps

  James Gorman, The New York Times  Published: 08 Apr 2021 12:48 PM BdST Updated: 08 Apr 2021 12:48 PM BdST A logo is pictured outside a building of the World Health Organisation (WHO) during an executive board meeting on update on the coronavirus outbreak, in Geneva, Switzerland, Feb 6, 2020. REUTERS The joint international and Chinese mission organised by the World Health Organization on the origins of COVID released its report last week suggesting that for almost every topic it covered, more study was needed. What kind of study and who will do it is the question. ); } The report suggested pursuing multiple lines of inquiry, focused on the likely origin of the coronavirus in bats. It concluded that the most likely route to humans was through an intermediate animal, perhaps at a wildlife farm. Among future efforts could be surveys of blood banks to look for cases that could have appeared be

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