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Phase 1 Clinical Trial Confirms HIV Vaccine Approach

Phase 1 Clinical Trial Confirms HIV Vaccine Approach by Angela Mohan on  February 4, 2021 at 11:12 AM Phase 1 clinical trial testing a novel vaccine against HIV has produced promising results, IAVI and Scripps Research announced. The vaccine showed success in stimulating production of rare immune cells needed to start the process of generating antibodies against the fast-mutating virus; the targeted response was detected in 97 percent of participants who received the vaccine. This study demonstrates proof of principle for a new vaccine concept for HIV, a concept that could be applied to other pathogens, as well, says William Schief, Ph.D., a professor and immunologist at Scripps Research and executive director of vaccine design at IAVI s Neutralizing Antibody Center, whose laboratory developed the vaccine.

Hebrew U Researchers Find Minuscule Worm May Hold Secret to Reversing Brain Damage | The Jewish Press - JewishPress com | Jewish Press News Desk | 22 Shevat 5781 – February 4, 2021

Dr. Ithai Rabinowitch A team of Hebrew University researchers have successfully used genetic engineering as a first step to what one day may allow scientists to genetically repair damaged brain circuits. The process, which was performed in tiny translucent C. elegans worms, saw the introduction of synthetically engineered connections (or synapses), as a means for bypassing missing connections between neurons in an impaired brain ( The team, led by Dr. Ithai Rabinowitch, a Neurobiologist in the Faculty of Medicine at Hebrew University, applied the genetically engineered bypass to repair a failed odor response in the worms due to neuronal loss. With the synthetic bypass network in place, the worms successfully responded to the odor stimuli, a behavior that was diminished in the absence of the genetically engineered “fix.” The study, published in Cell Systems was jointly led by Dr. Jihong Bai of the Fred Hutchinson Cancer Research Center in Seattle, Washington.

US rushes to catch up in the race to detect coronavirus mutations

US rushes to catch up in the race to detect coronavirus mutations By MIKE STOBBE and MARION RENAULT | February 4, 2021 at 6:18 AM HST - Updated February 4 at 8:22 AM NEW YORK (AP) Despite its world-class medical system and its vaunted Centers for Disease Control and Prevention, the U.S. fell behind in the race to detect dangerous coronavirus mutations. And it’s only now beginning to catch up. The problem has not been a shortage of technology or expertise. Rather, scientists say, it’s an absence of national leadership and coordination, plus a lack of funding and supplies for overburdened laboratories trying to juggle diagnostic testing with the hunt for genetic changes.

United States rushing to catch up in race to detect coronavirus mutations

United States rushing to catch up in race to detect coronavirus mutations
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US researchers rush to catch up in race to detect COVID-19 variants

US researchers rush to catch up in race to detect COVID-19 variants
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