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Baricitinib speeds COVID-19 recovery in NIAID trial

Tags » In a randomized, controlled trial of more than 1,000 adults hospitalized with COVID-19 pneumonia, treatment with the anti-inflammatory drug baricitinib resulted in faster recovery and a greater likelihood of clinical improvement, when combined with the antiviral drug remdesivir. The results of the international ACTT-2 (Adaptive COVID-19 Treatment Trial), sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, were published Friday Dec. 11 in the Baricitinib was originally developed by Eli Lilly and Company for rheumatoid arthritis and was FDA-approved for that indication in 2017. The drug, part of a class of drugs that inhibits JAK enzymes, received an emergency use authorization for COVID-19 treatment in November 2020, based upon the ACTT-2 results.

Grady memorial hospitalUnited statesUniversity of cincinnatiUniversity of nebraska medical centerAndre kalilAneesh mehtaVincent marconiNadine rouphaelEli lillyJohns hopkins universityVanderbilt university medical centerEmory universityNational institute of allergyInfectious diseases clinical research consortiumUniversity of alabama at birminghamNational emerging special pathogens training

These drugs might prevent severe Covid-19

updated: Dec 14 2020, 18:55 ist In the year since the Covid pandemic began, glimmers of hope have come on the horizon. Vaccines are on the way, and the percentage of patients who die has fallen in many places as doctors have learned how to save the sickest patients. These successes are not enough and they overshadow the more limited progress made toward developing drugs that could prevent mild cases of the disease from worsening. Such treatments are urgently needed because many people will get sick with Covid until vaccines induce enough herd immunity in the population to keep the infections under control.

United statesTimothy sheahanDonald trumpAnthony fauciDavid bakerAngela reiersenRachel bender ignacioWilliam fischerRidgeback biotherapeuticsRichard plemperGilead sciencesNational institute of allergyUniversity of north carolina at chapel hillUniversity of washingtonUniversity of north carolina school medicineResearchers at washington university in st

Collaboration Driving Progress: LLS Forms Alliances with Leading Cancer Institutions and Foundations to Co-Fund nearly $17 million in New Research Grants

Share this article Share this article RYE BROOK, N.Y., Dec. 14, 2020 /PRNewswire/ As the world confronts a viral pandemic not seen in the past 100 years, the reverberations are being felt across every sector, from healthcare to the economy, education, business and science, including the blood cancer community. Blood cancers don t stop for the Covid-19 virus and the urgent need for collaboration to address these challenges has never been starker. In response, The Leukemia & Lymphoma Society (LLS) today announced it has forged significant alliances with premier foundations, cancer institutions and philanthropic individuals, bringing their collective resources to bear to co-fund approximately $9 million in new research grants, with up to $8 million more funding anticipated over the next year. This cooperation will allow LLS to continue driving forward impactful research to find better treatments and cures for patients with leukemia, lymphoma, myeloma and other blood cancers.

United statesSouth australiaHarryt mangurian jrKimberly stegmaierJohanna melo cardenasJennifer trowbridgeFrederick lockeSylvain simonTherese vuStanford universityanddaniel thomasRavindra majetiLee greenbergerJohn pimandaAndrea greifRising tide foundation for clinical cancer researchNational cancer institute

Households are a high-risk setting for SARS-CoV-2 transmission

Households are a high-risk setting for SARS-CoV-2 transmission
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These Drugs Might Prevent Severe COVID

These Drugs Might Prevent Severe COVID
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United statesTimothy sheahanDonald trumpAnthony fauciDavid bakerAngela reiersenRachel bender ignacioWilliam fischerRidgeback biotherapeuticsRichard plemperGilead sciencesNational institute of allergyUniversity of north carolina at chapel hillUniversity of washingtonUniversity of north carolina school medicineResearchers at washington university in st