New study on immunotherapy resistance sanantoniopost.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sanantoniopost.com Daily Mail and Mail on Sunday newspapers.
New cocaine and oxycodone biobanks provide investigatory therapeutic targets for addiction
A major hurdle to developing new and effective treatments for drug addiction is better understanding how exactly it manifests itself before, during and after chronic use. In a paper published online in the April 21, 2021 issue of the journal
eNeuro, an international team of researchers led by scientists at University of California San Diego School of Medicine describe the creation of two unique collections of more than 20,000 biological samples collected from laboratory rats before, during and after chronic use of cocaine and oxycodone.
Developed by the Preclinical Addiction Research Consortium, located in the Department of Psychiatry at UC San Diego School of Medicine and at Skaggs School of Pharmacy and Pharmaceutical Sciences, the new cocaine and oxycodone biobanks include samples from 20 different organs, plus urine, blood and feces.
Clinical study identifies genetic changes in head-neck cancer, association with immunotherapy resistance
Clinical study identifies genetic changes in head-neck cancer, association with immunotherapy resistance
Last Updated: Tue, Apr 27th, 2021, 10:20:08hrs
Washington [US], April 27 (ANI): A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy. Through a series of surprises, we followed clues that focused more and more tightly on specific genetic imbalances and their role in the effects of specific immune components in tumour development, said co-principal investigator Webster Cavenee, PhD, Distinguished Professor Emeritus at the University of California San Diego School of Medicine.
Neural implant monitors multiple brain areas at once, provides new neuroscience insights eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
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A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy. Through a series of surprises, we followed clues that focused more and more tightly on specific genetic imbalances and their role in the effects of specific immune components in tumor development, said co-principal investigator Webster Cavenee, PhD, Distinguished Professor Emeritus at University of California San Diego School of Medicine. The genetic abnormalities we identified drive changes in the immune cell composition of the tumors that, in turn, dictates responsiveness to standard of care immune checkpoint inhibitors.