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His Bahrain Victorious team was in the thick of the action as a number of riders looked to attack the race on the road to Campo Felice.
It was when Mohoric was behind team-mate Gino Mader that the horror incident took place, however.
His wheel re-gripped on the tarmac, but Mohoric, 26, was sent into the curb before careering over the handlebars and coming down directly on his head.
Mohoric was seen clipping the inside of the left curb as the riders looked to form a breakaway
As a result of the contact, Mohoric was sent flying over his handlebars before coming down
A third consecutive below-par round on Saturday at Quail Hollow has former University of Kansas All-American Gary Woodland within striking distance at the Wells