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More body, organ donors give gifts of life

Across China: More body, organ donors give gifts of life

HEFEI, Aug. 15 (Xinhua) Thirty-seven elderly have registered to become body donors in a small community in east China Anhui Province since 2002, making local

1st China-Pak Pathology Study Session held for clinical academic exchange--China Economic Net

1st China-Pak Pathology Study Session held for clinical academic exchange--China Economic Net
en.ce.cn - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from en.ce.cn Daily Mail and Mail on Sunday newspapers.

Frontiers | A Novel Probable Pathogenic PSEN2 Mutation p Phe369Ser Associated With Early-Onset Alzheimer s Disease in a Chinese Han Family: A Case Report

Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China The pathogenesis of Alzheimer s disease is complex, and early-onset Alzheimer s disease (EOAD) is mostly influenced by genetic factors. Presenilin-1, presenilin-2 (PSEN2), and amyloid precursor protein are currently known as the three main causative genes for autosomal dominant EOAD, with the PSEN2 mutation being the rarest. In this study, we reported a 56-year-old Chinese Han proband who presented with prominent progressive amnesia, aphasia, executive function impairment, and depression 5 years ago. The 3-year follow-up showed that the patient experienced progressive brain atrophy displayed on magnetic resonance imaging (MRI) and dramatic cognitive decline assessed by neuropsychological evaluation. This patient was clinically diagnosed as EOAD based on established criteria. A heterozygous variant (NM 000447.2: c.1106T>C) of PSEN2 was identified for the first time in this patient and her

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