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Two immunologists say an intranasal Covid vaccine can elicit an immune response at the site of infection – the respiratory tract.
Intranasal vaccination, which is administered through the nose, is also needle-free, meaning that more people may be willing to get vaccinated.
Ultimately, using both intramuscular and intranasal Covid vaccines may be effective in combating Covid-19.
Out of the 108 Covid-19 vaccines that are currently undergoing clinical trials, only eight are delivered intranasally (through the nose) – the rest are mainly given intramuscularly (into the muscle).
Considering SARS-CoV-2, the respiratory virus that causes Covid-19, predominantly enters the nasal passage first (this is why testing for the virus involves nasal swabs), a nasal spray vaccine could be beneficial in the continued fight against Covid, say two immunologists from the University of Alabama at Birmingham (UAB).