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Biogen reveals new data for MS therapies Tysabri and Vumerity

Biogen reveals new data for MS therapies Tysabri and Vumerity New data comes ahead of FDA decision on company s controversial Alzheimer’s drug aducanumab Biogen has announced new data for its multiple sclerosis therapies Tysabri and Vumerity, including analyses of extended interval dosing (EID) and new real-world experience data. The data, presented at the virtual American Academy of Neurology (AAN) annual meeting, includes quality of life benefits and analyses of EID with Tysabri (diroximel fumarate). Researchers analysed patient-reported data on 12 different domains on the Neuro-QoL (Quality of Life in Neurological Disorders) questionnaire to ‘better understand clinically meaningful quality of life benefits’ following Tysabri treatment.

BTK Inhibitor Cuts Marker of Neuronal Damage in Relapsing MS

email article The investigational agent evobrutinib significantly reduced serum levels of neurofilament light chain (NfL) in patients with relapsing multiple sclerosis (MS), a post hoc analysis of a phase II trial showed. Treatment with the highly selective Bruton s tyrosine kinase inhibitor (BTK), which targets B cells and myeloid cells, at a dose of 75 mg twice daily resulted in a 16.8% decline in blood NfL levels versus no decline in patients assigned to placebo ( P

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