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Omecamtiv Mecarbil Has Biggest Benefit at Lowest EFs

May 18, 2021 When omecamtiv mecarbil is used in patients who have chronic heart failure with reduced ejection fraction (HFrEF), the greater beneficial impact on clinical outcomes is seen in those with lower ejection fractions, a secondary analysis of the placebo-controlled GALACTIC-HF trial shows. Among the prespecified subgroups in the trial, LVEF was the strongest modifier of the treatment effect, with larger reductions in the risk of HF events or CV death observed as values fell ( P = 0.004 for interaction). Reductions in NT-proBNP were greater at the lower end of the range, as well, John Teerlink, MD (San Francisco VA Medical Center and the University of California, San Francisco), reported during the recent virtual American College of Cardiology (ACC) 2021 Scientific Session.

Stanford universityUnited statesMount pleasantSan franciscoRobert harringtonJohn teerlinkUniversity of californiaAmerican heart associationAmerican college of cardiologyDrug administrationMd stanford universityMd san francisco va medical centerJournal of the american college cardiologyMd central michigan universityAmerican collegeHighly encouraging

Falling Through the Cracks on Rapid Troponin Testing Protocols

email article Transitioning high-sensitivity troponin testing protocols in the emergency department for suspected acute coronary syndrome can have some unintended consequences, studies showed. In a prospective multicenter trial from Australia, patients randomized to a 0/1-hour high-sensitivity cardiac troponin-T (hs-cTnT) protocol unmasked to the care team had similar all-cause mortality and MI at 12 months as those whose early levels were masked and were treated based on the standard protocol of 0/3-hour testing (5.0% vs 3.8%, HR 1.32, 95% CI 0.95-1.83). However, for those with an intermediate elevation in troponin of less than 29 ng/L the only group for whom results differed between the two trial arms, with reporting to

United statesPatrick ogaraChristian muellerAmerican college of cardiologyJournal of the american college cardiologyEuropean society of cardiologyUniversity hospital baselAmerican collegePatricko garaEuropean societyஒன்றுபட்டது மாநிலங்களில்கிறிஸ்துவர் முல்லர்அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல்இதழ் ஆஃப் தி அமெரிக்கன் கல்லூரி இருதயவியல்ஐரோப்பிய சமூகம் ஆஃப் இருதயவியல்பல்கலைக்கழகம் மருத்துவமனை பேசல்

Moderate therapeutic hypothermia does not improve neurological outcomes after cardiac arrest

Moderate therapeutic hypothermia does not improve neurological outcomes after cardiac arrest
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

Michelr leEmily hendersonAmerican college of cardiologyHeart instituteUniversity of ottawa heart instituteUniversity of ottawaAmerican collegeAnnual scientificStudy lead authorInterventional cardiologistOttawa heart instituteஎமிலி ஹென்டர்சன்அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல்இதயம் நிறுவனம்பல்கலைக்கழகம் ஆஃப் ஆடவா இதயம் நிறுவனம்பல்கலைக்கழகம் ஆஃப் ஆடவா

Rivaroxaban Reduces First and Total Ischemic Events in Patients with Peripheral Artery Disease

Rivaroxaban Reduces First and Total Ischemic Events in Patients with Peripheral Artery Disease
dicardiology.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from dicardiology.com Daily Mail and Mail on Sunday newspapers.

Rupert bauersachsJournal of the american college cardiologyAmerican college of cardiologyAmerican collegeDarmstadt clinicஇதழ் ஆஃப் தி அமெரிக்கன் கல்லூரி இருதயவியல்அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல்அமெரிக்கன் கல்லூரி

Real-World Data Confirm Excellent Results For Bicuspid Patients Treated With Edwards SAPIEN 3 TAVR

Real-World Data Confirm Excellent Results For Bicuspid Patients Treated With Edwards SAPIEN 3 TAVR
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

Raj makkarLarryl woodEdwards lifesciencesAmerican college of cardiologyExchange commissionSociety of thoracic surgeonsSecurities exchangeEdwards lifesciences corporationAmerican college of cardiology heart associationTranscatheter aortic valve replacementThoracic surgeonsAmerican collegeTranscatheter valve therapyInterventional cardiologyAssociate directorSmidt heart institute