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Sacubitril/valsartan not superior to valsartan for advanced heart failure

Patients with heart failure with reduced ejection fraction (HFrEF) did not have better health outcomes if they took sacubitril/valsartan combination therapy compared with valsartan alone, according to new data presented at the American College of Cardiology s 70th Annual Scientific Session.

Hyperinvasive care improves survival in refractory out-of-hospital cardiac arrest

A subgroup of patients who experienced an out-of-hospital cardiac arrest (OHCA) that did not respond to standard advanced cardiac life support (ACLS), were immediately transported to a cardiac care center, and placed on a device similar to a heart-lung bypass machine were more likely to have survived with good brain function six months later than similar patients who received standard care at the site where the OHCA occurred.

Additional data, feedback on hospital care did not improve heart failure outcomes

A program designed to improve hospital care for patients with heart failure, the leading cause of hospitalization among adults over age 65, did not bring additional benefits beyond existing hospital quality improvement programs in a randomized controlled trial presented at the American College of Cardiology s 70th Annual Scientific Session.

Sotagliflozin shows benefit for difficult-to-treat form of heart failure

Patients with both diabetes and heart failure who were treated with sotagliflozin, a novel investigational drug for diabetes, for a median of nine to 16 months experienced reductions of 22% to 43% in the risk of death or worsening heart failure compared with similar patients who were treated with a placebo, according to research presented at the American College of Cardiology s 70th Annual Scientific Session.

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