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Finerenone Cuts CV Events in CKD Patients With Diabetes: FIGARO-DKD

May 11, 2021 The addition of finerenone to standard medical therapy significantly reduces the risk of cardiovascular mortality and other cardiovascular events in patients with chronic kidney disease (CKD) and type 2 diabetes, according to topline results from FIGARO-DKD announced this week. Bayer, the maker of the investigational mineralocorticoid receptor antagonist (MRA), announced that the large-scale study met its primary endpoint reduction in the risk of first occurrence of CV mortality, MI, stroke, or heart failure hospitalization in the approximately 7,400 patients randomized in the trial. The positive study is the second trial showing a benefit of finerenone in patients with CKD and type 2 diabetes. In the FIDELIO-DKD trial, led by George Bakris, MD (University of Chicago, IL), finerenone reduced the risk of kidney failure or death from renal causes, the study’s primary endpoint, and reduced the risk of CV mortality, MI, stroke, or heart failure hospitalization. Unlike

George bakrisEuropean society of cardiology congressMd university of chicagoAmerican college of cardiologyEuropean medicines agencyDrug administrationEuropean societyAmerican collegeஜார்ஜ் பக்ரிஸ்ஐரோப்பிய சமூகம் ஆஃப் இருதயவியல் காங்கிரஸ்ம்ட் பல்கலைக்கழகம் ஆஃப் சிகாகோஅமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல்ஐரோப்பிய சமூகம்அமெரிக்கன் கல்லூரி

Hostility Is Common in Cardiology: Can a New ACC/AHA Statement Help?

The contemporary cardiology workplace is fraught with hostility, including discrimination and harassment, according to new data from a global survey. A very low response rate, however, raises questions as to why clinicians refrained from participating in the project. Also this week, the American College of Cardiology and American Heart Association (ACC/AHA), released a consensus report on professionalism and ethics that potentially could help rectify many of the issues hindering physician well-being in the workplace. The survey, published in the May 18, 2021, issue of the Journal of the American College of Cardiology, is far from the first to document a challenging culture in medicine generally and in cardiology specifically. But lead author Garima Sharma, MD (Johns Hopkins University School of Medicine, Baltimore, MD), told TCTMD it is the first to consolidate international perspectives: from Africa, Asia, the Caribbean, Eastern Europe, the European Union, the Middle East, O

United statesNew south walesWestern australiaSonya burgessP sonya burgessPurvi parwaniC michael valentineGarima sharmaJaved butlerLoma linda universityAmerican heart associationMd university of virginiaAmerican college of cardiologyUniversity of sydneyMd johns hopkins university school of medicineUniversity of new south wales

Efficacy Of Repatha® Across High-Risk Patient Populations Reinforced At ACC 21

Amgen today announced the presentation of four cardiovascular research abstracts, including final data from the Repatha ® open label extension trial of patients living with HIV who have high cholesterol, as well as new data from FOURIER evaluating biomarkers of major cardiovascular events, including complex revascularization procedures. Additional abstracts to be presented include a simulation comparing the impact … Amgen (NASDAQ:AMGN) today announced the presentation of four cardiovascular research abstracts, including final data from the Repatha ® (evolocumab) open label extension trial of patients living with HIV who have high cholesterol, as well as new data from FOURIER evaluating biomarkers of major cardiovascular (CV) events, including complex revascularization procedures. Additional abstracts to be presented include a simulation comparing the impact of different LDL-C guidelines on CV risk reduction, as well as negative control outcomes to assess residual bias when compa

Puerto ricoMichael strapazonMegan foxAmgen medinfoDavidm reeseAmerican college of cardiologyDrug administrationWorld health organizationBeigene ltdProgram to reduceExchange commissionEuropean unionAmerican collegeAnnual scientific sessionCardiovascular outcomes following inhibitionAccelerating lipid lowering post

Moderate Alcohol Tied to Lower Stress-Related Brain Activity, MACE

Moderate Alcohol Tied to Lower Stress-Related Brain Activity, MACE
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United statesUniversity of washingtonEugene yangBrigham biobankKenechukwu mezuePrevention of cardiovascular disease councilAmerican college of cardiologyHarvard medical schoolMassachusetts general hospitalAmerican collegeMedscape cardiologyCardiovascular diseaseMassachusetts general brigham biobankஒன்றுபட்டது மாநிலங்களில்பல்கலைக்கழகம் ஆஃப் வாஷிங்டன்யூஜின் யாங்

Revisit of ISCHEMIA Bolsters Conservative Message in Stable CAD

Revisit of ISCHEMIA Bolsters Conservative Message in Stable CAD
medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.

United statesNew zealandNorth carolinaDuke universityHarveyd whiteEli lillyOtsuka pharmaceuticalsDuke university school of medicineAmerican college of cardiologyCardiovascular servicesArbor pharmaceuticalsImbria pharmaceuticalsMilestone pharmaceuticalsUniversity of aucklandGreen lane cardiovascular servicesAuckland city hospital