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American Cancer Society Names Dr Karen Knudsen as its Next CEO

Study provides new insights into resistance to immune checkpoint inhibitors

Novel immunotherapy approach may offer therapeutic advantages for melanoma

Novel immunotherapy approach may offer therapeutic advantages for melanoma In a new study led by Yale Cancer Center, researchers have advanced a tumor-targeting and cell penetrating antibody that can deliver payloads to stimulate an immune response to help treat melanoma. The study was presented today at the American Association of Cancer Research (AACR) virtual annual meeting. Most approaches rely on direct injection into tumors of ribonucleic acids (RNAs) or other molecules to boost the immune response, but this is not practical in the clinic, especially for patients with advanced cancer. In this study, we can deliver immune stimulatory RNA to tumors in vivo following systemic administration.

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