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Shattuck Labs Reports Fourth Quarter and Full Year 2020 Financial Results and Recent Business .
Shattuck Labs, Inc.March 15, 2021 GMT
– Initial dose-escalation data from Phase 1 clinical trial for lead wholly owned CD47 checkpoint inhibitor, SL-172154 (SIRPα-Fc-CD40L), expected in the second half of 2021 –
– Dose-escalation data from Phase 1 clinical trial for lead partnered PD-1 checkpoint inhibitor, SL-279252 (PD1-Fc-OX40L), expected in the second half of 2021 –
AUSTIN, TX and DURHAM, NC, March 15, 2021 (GLOBE NEWSWIRE) Shattuck Labs, Inc. (Shattuck) (NASDAQ: STTK ), a clinical-stage biotechnology company pioneering the development of bi-functional fusion proteins as a new class of biologic medicine for the treatment of patients with cancer and autoimmune disease, today reported financial results for the fourth quarter and full year ended December 31, 2020 and provided r
Cancer cells may dodge chemotherapy by going into active hibernation
Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of active hibernation that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study by scientists at Weill Cornell Medicine. These findings have implications for developing new drug combinations that could block senescence and make chemotherapy more effective.
In a study published Jan. 26 in
Cancer Discovery, a journal of the American Association for Cancer Research, the investigators reported that this biologic process could help explain why cancers so often recur after treatment. The research was done in both organoids and mouse models made from patients samples of acute myeloid leukemia (AML) tumors. The findings were also verified by looking at samples from AML patients that were collected throughout the course of treatment and
Study suggests that cancer cells may evade chemotherapy by going dormant edexlive.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from edexlive.com Daily Mail and Mail on Sunday newspapers.
Cancer cells may evade chemotherapy by going dormant, suggests study ANI | Updated: Mar 13, 2021 11:24 IST
Washington [US], March 13 (ANI): Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of active hibernation that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study.
The study was led by scientists at Weill Cornell Medicine. These findings have implications for developing new drug combinations that could block senescence and make chemotherapy more effective.
In a study published Jan. 26 in Cancer Discovery, a journal of the American Association for Cancer Research, the investigators reported that this biologic process could help explain why cancers so often recur after treatment. The research was done in both organoids and mouse models made from patients samples of acute myeloid leukaemia (AML) tumours. T
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Incyte (Nasdaq:INCY) today announced that multiple abstracts from across its oncology portfolio will be presented during Week 1 of the upcoming American Association for Cancer Research (AACR) Annual Meeting 2021, held virtually from April 10-15, 2021.
“At AACR 2021, we look forward to sharing clinical and pre-clinical data from INCB106385, our novel A2A/A2B adenosine receptor antagonist, and INCA00186, our novel CD73 monoclonal antibody both of which highlight our ongoing efforts targeting the adenosine pathway. Presentations at the congress will also feature updated data from our LIMBER development program, including results from our Phase 2 combination study of ruxolitinib, a janus kinase (JAK1/JAK2) inhibitor, and parsaclisib, a potent, highly selective oral inhibitor of phosphatidylinositol 3-kinase delta (PI3Kδ),” said Steven Stein, M.D., Chief Medical Officer, Incyte, adding, “We further look