Taking Immune-Boosting Drug Before Lung Cancer Surgery Boosts Response Rates: Study
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Researchers tested the effects of using Opdivo with chemotherapy before cancer surgery
The combination therapy yielded higher response rates
Using an immune-system boosting drug along with chemotherapy before undergoing lung cancer surgery may help increase response rates, doctors say.
As part of a study, called the CheckMate-816 trial, a team of doctors looked at the effects of using an immune-boosting drug, Opdivo, along with chemotherapy in patients with early-stage non-small cell lung cancer (NSCLC), Fierce Pharma
At a meeting of the American Association for Cancer Research on Saturday, the team reported that 24% of those who used Opdivo along with chemotherapy before the surgery showed no signs of cancer cells in the tissues after the procedure. By comparison, the rate was 2.2% among those who received only chemotherapy prior to the procedure.
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GeneLeap Presents New Preclinical Data for Hydrogel Encapsulated TLR9 Agonist at AACR 2021
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BOSTON, April 14, 2021 /PRNewswire/ GeneLeap Bio., a subsidiary of Luye Life Sciences specializing in the development of nucleic acid therapeutics, presented an ePoster entitled Hydrogel encapsulated TLR9 agonists show sustained tumor growth inhibition and prolong survival of CT26 tumor-bearing mice at the American Association for Cancer Research 2021 Annual Meeting. The preclinical study shows that compared with using TLR9 agonist on its own, a hydrogel encapsulated TLR9 agonist, independently developed by GeneLeap Biotech, can significantly improve antitumor performance, while demonstrating tumor growth inhibitory effects similar to that of TLR9 agonist without hydrogel encapsulation.
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