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Data-driven Derivation and Validation of Novel Phenotypes for Acute Kidney Transplant Rejection using Semi-supervised Clustering

Data-driven Derivation and Validation of Novel Phenotypes for Acute Kidney Transplant Rejection using Semi-supervised Clustering
asnjournals.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asnjournals.org Daily Mail and Mail on Sunday newspapers.

France generalUnited statesDirk kuypersMaud rabeyrinMarie paule emondsOlivier thaunatAleksandar senevMaarten naesensEvelyne lerutThibaut vauletJasper callemeynEthical committee of the university hospitals leuvenLeuven university hospitalsAdvisor for the european medicines agencyAdvisory committeeParis transplant group

COVID-19 and AKI: Where Do We Stand?

COVID-19 and AKI: Where Do We Stand?
asnjournals.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asnjournals.org Daily Mail and Mail on Sunday newspapers.

United statesNew yorkNational kidney foundationAmerican society of nephrologyDepartment of veterans affairsChina medical treatment expert group for covidVeterans affairsNew york cityKidney precision medicine projectNational instituteKidney diseasesDeputy editorNational kidneyAmerican societyOpen accessChina medical treatment expert group

Columbia researchers develop kidney disease-spotting algorithm

Photo by Steve Dabenport/Getty Images Researchers at Columbia University Vagelos College of Physicians and Surgeons have developed an algorithm that automatically scours electronic health records to alert physicians to early-stage chronic kidney disease. The algorithm searches EHRs for results of blood and urine tests before performing calculations to indicate kidney function and damage and alerting clinicians. Identifying kidney disease early is of paramount importance, because we have treatments that can slow disease progression before the damage becomes irreversible, said study leader Dr. Krzysztof Kiryluk, associate professor of medicine, in a statement to press. WHY IT MATTERS More than one in seven adults is estimated to have chronic kidney disease, according to the U.S. Centers for Disease Control and Prevention, but as many as 90% don t know they have it.

United statesKat jercichKrzysztof kirylukUs centers for diseaseUs department of healthHuman servicesAmerican society of nephrologyColumbia university vagelos collegeDisease controlLatinx americansDigital medicineAmerican societyஒன்றுபட்டது மாநிலங்களில்எங்களுக்கு மையங்கள் க்கு நோய்எங்களுக்கு துறை ஆஃப் ஆரோக்கியம்மனிதன் சேவைகள்

Vadadustat Matches Standard for CKD-Related Anemia, With Caveat

email article The investigational hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor vadadustat was noninferior to the erythropoiesis-stimulating agent darbepoetin alfa for treating anemia in chronic kidney disease (CKD) patients, a pair of phase III trials found. 2TECT Study of non-dialysis-dependent CKD treatment with vadadustat met the pre-specified noninferiority endpoint for hematologic efficacy compared with darbepoetin alfa, reported Glenn Chertow, MD, MPH, of Stanford University School of Medicine in California, and colleagues. Looking only at ESA-untreated patients, there was an average between-group hemoglobin concentration difference of 0.05 g/dL (95% CI -0.04 to 0.15) maintained from weeks 24 to 36 with vadadustat or darbepoetin alfa treatment.

United statesNew yorkUnited kingdomBritish columbiaStanford universityGlenn chertowKai uwe eckardtAdeera levinUniversity of british columbiaAmerican society of nephrologyStanford university school of medicineStanford university schoolNew england journalAmerican societyKidney weekAkebia therapeutics

COVID-19 survivors face higher risk of death and serious illness

COVID-19 survivors including those not sick enough to be hospitalized have an increased risk of death in the six months following diagnosis with the virus, researchers report. As the COVID-19 pandemic has progressed, it has become clear that many survivors even those who had mild cases continue to manage a variety of health problems long after the initial infection should have resolved. The researchers have catalogued the numerous diseases associated with COVID-19, providing a big-picture overview of the long-term complications of COVID-19 and revealing the massive burden this disease is likely to place on the world’s population in the coming years.

District of columbiaUnited statesZiyad al alyWashington university school of medicineUs department of veterans affairsVeterans health administrationAmerican society of nephrologyInstitute for public health at washington universityLouis health care systemVeterans affairs stEducation serviceClinical epidemiology centerWashington university schoolVeterans affairsLouis health carePublic health