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 E-Mail IMAGE: Lead author of the study, Dr. Kelsey Collins is a postdoctoral fellow in Guilak s laboratory. view more  Credit: Shriners Hospitals for Children (St. Louis) - A new study by investigators at the Shriners Hospital for Children St. Louis suggests the damaging effects of obesity are not due to body weight but rather come from something much smaller - biochemical signals released by fat cells. The study focuses on the link between overweight or obesity and the development of osteoarthritis, a painful disease of the joints. The investigation was led by Dr. Farshid Guilak, director of the St. Louis Shriners Hospital Research Center.

Kelsey collinsFarshid guilakNational institutes of healthNational institute of arthritisNational institute onWashington university school of medicineWashington university centerProceedings of the national academy sciencesLouis shriners hospital research centerNancy taylor foundation for chronic diseasesArthritis foundationShriners hospitalLouis shriners hospital researchOrthopaedic surgeryWashington universityLouis shriners