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Cardiovascular disease risk profile and management practices in 45 low-income and middle-income countries: A cross-sectional study of nationally representative individual-level survey data

Research Article Cardiovascular disease risk profile and management practices in 45 low-income and middle-income countries: A cross-sectional study of nationally representative individual-level survey data David Peiris , Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing Affiliations The George Institute for Global Health, UNSW Sydney, New Delhi, India, Manipal Academy of Higher Education, Manipal, India Roles Formal analysis, Methodology, Writing – review & editing Affiliation Heidelberg Institute of Global Health, Medical Faculty and University Hospital, University of Heidelberg, Heidelberg, Germany Roles Conceptualization, Data curation, Methodology, Writing – review & editing Affiliation Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America

Kids blood pressure measurements different between arms, potential for misdiagnosis

 E-Mail IMAGE: Blood pressure measurements in children and adolescents should be taken from both arms after new research showed substantial differences could be seen depending on which arm was used. view more  Credit: Marcelo Leal Blood pressure measurements in children and adolescents should be taken from both arms after new research showed substantial differences could be seen depending on which arm was used. The study, led by the Murdoch Children s Research Institute (MCRI) and published in the Journal of Hypertension, found even a small difference in blood pressure measurements between arms could lead to a wrong diagnosis. MCRI PhD candidate and study lead author Melanie Clarke said this was the first study worldwide to determine the size and frequency of inter-arm blood pressure differences in children and adolescents.

New type of bone cell could reveal targets for osteoporosis treatment

 E-Mail Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may reveal new therapeutic approaches for osteoporosis and other skeletal diseases. The new cells, which the researchers term osteomorphs , are found in the blood and bone marrow, and fuse together to form osteoclasts, specialised cells that break down bone tissue. They have a unique genomic profile that reveals promising and as yet unexplored targets for therapy. This discovery is a game-changer, which not only helps us understand bone biology but presents significant new in-roads for osteoporosis therapy, says co-senior author Professor Tri Phan, who heads the Intravital Microscopy and Gene Expression Lab at the Garvan Institute. Osteomorphs express several genes that seem to be linked to bone disease, which could lead scientists to entirely new ways to target osteoporosis.

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