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Scientists discover jumping genes that can protect against blood cancers

 E-Mail IMAGE: Zhimin Gu, Ph.D., postdoctoral fellow, Children s Medical Center Research Institute at UT Southwestern (CRI), and Jian Xu Ph.D., associate professor, CRI view more  Credit: UT Southwestern Medical Center DALLAS - April 8, 2021 - New research has uncovered a surprising role for so-called jumping genes that are a source of genetic mutations responsible for a number of human diseases. In the new study from Children s Medical Center Research Institute at UT Southwestern (CRI), scientists made the unexpected discovery that these DNA sequences, also known as transposons, can protect against certain blood cancers. These findings, published in Nature Genetics, led scientists to identify a new biomarker that could help predict how patients will respond to cancer therapies and find new therapeutic targets for acute myeloid leukemia (AML), the deadliest type of blood cancer in adults and children.

Physician-Led Webinar Sponsored by Perimeter Medical Imaging AI Highlights Advancements in Intraoperative Specimen Imaging

Physician-Led Webinar Sponsored by Perimeter Medical Imaging AI Highlights Advancements in Intraoperative Specimen Imaging Prestigious panel of physician experts provide commentary on Perimeter’s potentially transformative and disruptive “OCT” technology Perimeter Medical Imaging AI, Inc. a medical technology company driven to transform cancer surgery with ultra-high-resolution, real-time, advanced imaging tools to address high unmet medical needs, today announced that a physician-led webinar organized by Perimeter as an industry … Prestigious panel of physician experts provide commentary on Perimeter’s potentially transformative and disruptive “OCT” technology Perimeter Medical Imaging AI, Inc. (TSX-V:PINK)(OTC:PYNKF) (FSE:4PC) (“Perimeter” or the “Company”), a medical technology company driven to transform cancer surgery with ultra-high-resolution, real-time, advanced imaging tools to address high unmet medical needs, today announced that a physician-led


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Study finds why some cancer drugs may be ineffective

 E-Mail A possible explanation for why many cancer drugs that kill tumor cells in mouse models won t work in human trials has been found by researchers with The University of Texas Health Science Center at Houston (UTHealth) School of Biomedical Informatics and McGovern Medical School. The research was published today in Nature Communications. In the study, investigators reported the extensive presence of mouse viruses in patient-derived xenografts (PDX). PDX models are developed by implanting human tumor tissues in immune-deficient mice, and are commonly used to help test and develop cancer drugs. What we found is that when you put a human tumor in a mouse, that tumor is not the same as the tumor that was in the cancer patient, said W. Jim Zheng, PhD, professor at the School of Biomedical Informatics and senior author on the study. The majority of tumors we tested were compromised by mouse viruses.

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