Immune cells in the meninges come from bone marrow in the skull and migrate to the brain through special channels without passing through the blood. These immune cells help to guard the brain and spinal cord against inflammation and infection.
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Finding alternatives to traditional antibiotics aim of $11 million grant
Researchers at Washington University School of Medicine in St. Louis have received an $11 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) to find new ways to combat the growing threat of antibiotic resistance.
The grant funds a two-pronged approach. One aims to identify and develop alternatives to antibiotics for urinary tract infections (UTIs) and other infections caused by drug-resistant bacteria. The other is exploring the potential for antibiotic development of GmPcides, a novel class of molecules that kills a wide variety of bacteria in the lab when used alone, and boosts the bacteria-killing properties of other antibiotics when used in combination with them.
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