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 E-Mail PHILADELPHIA A retrospective study led by researchers from Penn Medicine found that with MitraClip for treatment of secondary mitral regurgitation (MR), a heart disease associated with problems in the left ventricle, there was no negative effect of having a slightly smaller mitral valve opening as long as there was good reduction of the mitral regurgitation. The study is published today in JACC: Cardiovascular Interventions. This data is very reassuring for physicians who place MitraClips in patients with secondary mitral regurgitation. It demonstrates that the benefits of MR reduction in patients with heart failure were maintained even when mild-to-moderate mitral stenosis, which can be caused by a narrowing of the mitral valve, occurred after MitraClip, said lead author Howard C. Herrmann, MD, the John Winthrop Bryfogle Professor of Cardiovascular Diseases in the Perelman School of Medicine at the University of Pennsylvania and Health System Director for Interventi

University of pennsylvaniaUnited statesHowardc herrmannJohn winthrop bryfogleSuveeksha naiduHealth systemNational institutes of healthUniversity of pennsylvania health systemPerelman school of medicineRuth perelman school of medicineCardiovascular research foundationPenn medicineJohn winthrop bryfogle professorCardiovascular diseasesPerelman schoolHealth system director