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Drug supply chain vulnerabilities have achieved greater visibility with the COVID-19 pandemic, but they have increasingly plagued countries in the past few years. A survey published in
Health Policy s December issue found that 20 of 24 countries used drug registries to combat them, 20 simplified regulatory procedures during shortages, 18 regularly talked with stakeholders, and 15 had financial sanctions in place for when manufacturers missed notification or supply requirements.
Even with these practices in place, multiple countries expressed an interest in increasing management strategies, and for good reason. Finland, the researchers report, experienced an 18-fold increase in shortages from 2010 to 2018, with instances doubling from 2016 to 2018 alone.
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During the early months of the COVID-19 pandemic, azithromycin was one of the virus s unproven, potential treatments, and the resulting shortage forced US doctors to rely on the substitute drug clarithromycin as an adjunct surgical prophylaxis for preventing endometritis in non-elective cesarean deliveries. Now, new research findings reveal that the option is a safe alternative.
In a recent study published by
PLOS One, 4.5% of healthy women who were given clarithromycin and needed cesarean deliveries developed endometritis compared with 11.2% of those who didn t receive any adjunct macrolide prophylaxis (crude analysis,
P = 0.025).
Postpartum endometritis is a womb infection with a 1% to 3% incidence rate after vaginal delivery, but anywhere from a 13% to 90% incidence rate after cesarean delivery, according to Medscape.
Experts: Telehealth Will Play an Important Post-Pandemic Role in Pharmacy Practice pharmacytimes.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pharmacytimes.com Daily Mail and Mail on Sunday newspapers.