Risk Factors of Experiencing Side Effects of Cancer Treatment by Angela Mohan on April 7, 2021 at 12:08 PM
Psycho-Oncology, which includes 24 studies.
Steroids are essential for treating children with acute lymphoblastic leukemia, a type of cancer of the blood and bone marrow, but they can cause severe side effects such as psychological reactions and sleep problems.
However, evidence suggests that the type and dose of steroids are not related to psychological reactions, but may be related to sleep problems. Younger patients seem at risk for behavioral problems and older patients for sleep problems. There is a lot to gain in the prevention and treatment of steroid-induced psychological and sleep problems, and recognition comes first, said senior author Raphaële R.L. van Litsenburg, MD, PhD, of the Princess Máxima Center in The Netherlands. A standardized registration of these side effects and their risk factors is warranted for future studies.
Cancer Patients With COVID-19 Have Similar Immune Response To People Without Cancer medindia.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medindia.net Daily Mail and Mail on Sunday newspapers.
Antibodies Deplete Cancer Cells in Mice and Human Cell Lines by Angela Mohan on March 2, 2021 at 12:14 PM
Science,
Science Immunology.
Some immunotherapy approaches against cancers rely on common cancer-related mutations to serve as antigens; they instigate an immune response to the cancer.
Although it is one of the most common mutant tumor suppressor genes known in human cancers, the cancer-related p53 tumor suppressor gene has not been successfully targeted via this approach.
In
Science, Emily Han-Chung Hsiue and colleagues successfully engineered a bispecific antibody to reactivate p53. Hsiue et al. first identified a distinct targetable fragment of the mutant tumor suppressor protein and characterized the structural basis for how the fragment is presented to T cells.
Urinalysis: A Game Changer in Early Cancer Diagnosis medindia.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medindia.net Daily Mail and Mail on Sunday newspapers.
Knowing DNA Repair Toolkit to Chart Cancer Evolution by Angela Mohan on February 18, 2021 at 3:40 PM
Deficiencies in DNA repair pathways increase the instability of the genes, and this causes cancer to develop.
Therefore, detailed knowledge of how DNA repair pathways participate in this process is crucial for tracking tumor progression, understanding the emergence of drug resistance, and developing efficient therapeutic interventions.
To this end, a group of scientists from China examined five critical DNA repair pathways and their impact on cancer evolution by reviewing the findings of the latest published research. So, it is not surprising that particularly defective DNA repair pathways are associated with specific cancers.