0 to 10: HR 2.54 (95% CI 1.44-4.50)
11 to 25: HR 1.64 (95% CI 1.23-2.18)
>25: HR 1.48 (95% CI 1.10-1.98) This study suggests that Black women in the U.S. with ER-positive,
ERBB2-negative, axillary lymph node-negative breast cancer are more likely to have a high-risk RS [recurrence score] and to experience breast cancer-specific mortality compared with non-Hispanic white women within the same risk group, Hoskins and co-authors wrote. In addition, the RS provides less prognostic information for Black women.
Accuracy of the 21-gene recurrence score was significantly worse for Black women (C index 0.656, 95% CI 0.592-0.720) versus non-Hispanic white women (C index 0.700, 95% CI 0.677-0.722;
P=0.002). The findings suggest that Black women disproportionately develop aggressive ER-positive tumors and that the Oncotype DX Breast Recurrence Score test incompletely defines prognosis in these women, the authors wrote. Genomic prognostic assays may require recalibration for racia
Sore and Itchy eyes indicate Covid-19: Study
File photo - Murali Kumar K×
Face
masks have, now, become a part of our daily gear for protection against airborne pathogens, which enter our bodies through our nose and mouth.
Photophobia, sore eyes, and itchy eyes can indicate Covid 19, according to a study published in the
British Medical Journal (BMJ).
Professor
Shahina Pardhan, Lead Author, Director of the Institute of Vision and Ayear Research at ARU, said, This is the first study to examine the various eye symptoms of conjunctive disease in connection with Covid-19 its time frame, and its duration.” While
New Era of Partnership Between Yeshiva University and Montefiore Medicine
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NEW YORK, Jan. 19, 2021 /PRNewswire/ Dr. Ari Berman and Dr. Philip Ozuah signed a new agreement between Yeshiva University and Montefiore Medicine launching a joint Yeshiva University-Albert Einstein College of Medicine B.A./B.S.-M.D. program for highly qualified high school graduates ensuring their path to an excellent medical education and an impactful career in healthcare. Yeshiva University and Einstein have also created a task force to study the creation of joint academic and career-related programs in the fields of healthcare and health sciences.
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Some 613 homeless New Yorkers died between July of 2019 and June of 2020, a 52% increase compared to the prior fiscal year, according to data released Tuesday by the de Blasio administration, a grim indicator of the effect of the coronavirus on people lacking permanent housing.
The largest number of those deaths occurred between April and June, when COVID-19 first began to bear down on the city. As infections grew and communities of color were devastated by the pandemic, so was the city’s vast shelter system, where single adults typically share a room with several others.
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IMAGE: The synthesis of the potent antibiotic thiostrepton uses a radical SAM protein TsrM, whose crystal structure is shown at left while bound to an iron-sulfur cluster and cobalamin. New images. view more
Credit: Booker Lab, Penn State
UNIVERSITY PARK, Pa. Images of a protein involved in creating a potent antibiotic reveal the unusual first steps of the antibiotic s synthesis. The improved understanding of the chemistry behind this process, detailed in a new study led by Penn State chemists, could allow researchers to adapt this and similar compounds for use in human medicine. The antibiotic thiostrepton is very potent against Gram-positive pathogens and can even target certain breast cancer cells in culture, said Squire Booker, a biochemist at Penn State and investigator with the Howard Hughes Medical Institute. While it has been used topically in veterinary medicine, so far it has been ineffective in humans because it is poorly absorbed. We studied