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Do purines influence cancer development?

Credit: Laura Alvarez, CeMM Numerous disease development processes are linked to epigenetic modulation. One protein involved in the process of modulation and identified as an important cancer marker is BRD4. A recent study by the research group of Giulio Superti-Furga, Principal Investigator and Scientific Director at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, now shows that the supply of purines as well as the purine synthesis of a cell can influence BRD4 activity and thus play a role in the carcinogenesis process. The findings were published in Nature Metabolism. Chromatin is a central component of the cell nucleus. It refers to the complex of the approximately two-meter-long human DNA with proteins that organize it so that - depending on the cell type - certain genes are activated or deactivated. In order to be able to adapt to diverse situations and influences, cells read the information relevant to them from the DNA. If this process

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Kathleen Folbigg, Australian mom convicted of killing her 4 babies, fights for release, citing genetics

Kathleen Folbigg, Australian mom convicted of killing her 4 babies, fights for release, citing genetics
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United statesUnited kingdomNew south walesKathleen folbiggCraig folbiggAustralian academy of scienceAssociated pressCessnock correctional centerAustralian academyAustralian storyஒன்றுபட்டது மாநிலங்களில்ஒன்றுபட்டது கிஂக்டம்புதியது தெற்கு வேல்ஸ்ஆஸ்திரேலிய கலைக்கழகம் ஆஃப் அறிவியல்தொடர்புடையது ப்ரெஸ்ஆஸ்திரேலிய கலைக்கழகம்

Measuring time accurately increases the entropy in the universe

Bruce Rolff/Alamy Keeping time accurately comes with a price. The maximum accuracy of a clock is directly related to how much disorder, or entropy, it creates every time it ticks. Natalia Ares at the University of Oxford and her colleagues made this discovery using a tiny clock with accuracy that can be controlled. The clock consisted of a 50-nanometre thick membrane of silicon nitride, vibrated by an electric current. Each time the membrane moved up and down once and then returned to its original position, the researchers counted a tick, and the regularity of the spacing between the ticks represented the accuracy of the clock.

Marcus huberBruce rolff alamyUniversity of oxfordAustrian academy of sciencesMark mitchison at trinity college dublinScientist default imageAustrian academyMark mitchisonTrinity college dublinபல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட்ஆஸ்திரேலிய கலைக்கழகம் ஆஃப் அறிவியல்விஞ்ஞானி இயல்புநிலை படம்ஆஸ்திரேலிய கலைக்கழகம்திரித்துவம் கல்லூரி டப்ளின்

Serial killer mum convicted of killing her four kids could be innocent, scientists claim

Serial killer mum convicted of killing her four kids could be innocent, scientists claim Australian serial killer Kathleen Folbigg has petitioned for a pardon which has been backed by experts, who say she could have been the victim of a miscarriage of justice Kathleen Folbigg, convicted of killing her four children, could be innocent according to scientists (Image: AAP/PA Images) The Daily Star s FREE newsletter is spectacular! Sign up today for the best stories straight to your inboxInvalid EmailSomething went wrong, please try again later. Sign up today! When you subscribe we will use the information you provide to send you these newsletters. Your information will be used in accordance with ourPrivacy Notice.

Kathleen folbiggTracy chapmanJohn shineCaleb gibsonSarah kathleenJustice reginald blanchPatrick allenLaura elizabethAustralian academy of scienceDaily starNew south walesJozef geczசுவடு சாப்மேன்ஜான் பிரகாசிக்கவும்காலேப் கிப்சன்சாரா க்யாத்லீந்

Kathleen Folbigg: Australian mother convicted of killing her four children petitions for a pardon

Isle of Wight Radio 10:00am - 3:00pm Live and Local Podcast - Supporting Live Local Music On The Isle Of Wight Kathleen Folbigg: Australian mother convicted of killing her four children petitions for a pardon An Australian woman who was convicted of killing her four children 18 years ago has petitioned the New South Wales governor for a pardon. Kathleen Folbigg, 53, was convicted on three charges of murder and one of manslaughter in 2003 and was sentenced to 30 years in prison. But dozens of scientists have backed her claims that her children died from natural causes and claim she could be the victim of a tragic miscarriage of justice.

Justice reginald blanchKathleen folbiggTracy chapmanAlan williamsJohn shineCraig folbiggSally clarkeAustralian academy of scienceNew south walesJozef geczMrs clarkLord goldsmithSky newsநீதி ரெஜினோல்ட் பிளான்ச்சுவடு சாப்மேன்ஆலன் வில்லியம்ஸ்