Page 10 - இணை ப்ரிந்ஸிபல் புலனாய்வாளர் News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Researchers identify genetic abnormalities that drive invasiveness in head and neck cancer A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy. Through a series of surprises, we followed clues that focused more and more tightly on specific genetic imbalances and their role in the effects of specific immune components in tumor development. Webster Cavenee, PhD, Co-Principal Investigator, Distinguished Professor Emeritus, University of California San Diego School of Medicine The genetic abnormalities we identified drive changes in the immune cell composition of the tumors that, in turn, dictates responsiveness to standard of care immune checkpoint inhibitors.

United statesSan diegoUniversity of california san diegoScottm lippmanWebster caveneeSteve dubinettEmily hendersonNational cancer instituteJonsson comprehensive cancer centerMd anderson cancer centerYork university langone health teresa davoliProceedings of the national academy sciencesUc san diego healthUc san diego moores cancer centerNational cancerCaris life sciences