Higher pulse pressure in smokers may signal cardiovascular disease risk
Karen Schmidt, American Heart Association News
April 27, 2021
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Consistent cigarette smoking has a small but significant effect on pulse pressure, according to research that suggests a possible new link between smoking and cardiovascular disease, especially among Black and white women.
Pulse pressure is the difference between systolic blood pressure, the top number in a reading, and diastolic blood pressure, the lower number. As that gap widens, it s problematic, said study co-author Kara Whitaker, assistant professor of health and human physiology at the University of Iowa in Iowa City.
It is measured by mmHg, which is a millimeter of mercury. So, for someone with a blood pressure reading of 120/80, the pulse pressure would be the difference between the two numbers, or 40 mmHg. The normal range is 40 to 60.
Higher pulse pressure in smokers may signal cardiovascular disease risk
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Certain treatments were more effective than others for people with intermittent claudication, but medium-term benefits did not persist in the long run, according to a network meta-analysis.
Treatments for peripheral artery disease (PAD) were associated with varying improvements in maximum walking distance (in meters) compared with controls across 46 randomized trials (N 4,256):
Short-term improvement ( 1 year) was observed with home exercise therapy (mean difference [MD] 89.4 m), supervised exercise therapy (MD 186.8 m), and supervised exercise therapy plus endovascular revascularization (MD 326.3 m)
Moderate-term improvement (1-2 years) was observed with supervised exercise therapy (MD 201.1 m) and supervised exercise therapy plus endovascular revascularization (MD 368.5 m)