India News: First-dose recipients of Covaxin don't need to restart their vaccination schedule if the gap between doses goes beyond the recommended 4-6 week interv
The first dose remains in the body but also has its own limited half-life. All antibodies produced are proteins that get degraded within the body whether used or not used. “So, the immune response generated by the first dose may possibly start tapering off after 4-5 months,” Bal added. The duration between two Covishield doses was increased from 4 weeks to 12 weeks primarily based on data from international trials where after a first dose the immune response was measured until the second dose was given. “In some cases, due to trial related issues, the second dose was given as late as 12 weeks and still the effect of the first dose was pretty much okay,” she added.
The first dose remains in the body but also has its own limited half-life. All antibodies produced are proteins that get degraded within the body whether used or not used. “So, the immune response generated by the first dose may possibly start tapering off after 4-5 months,” Bal added. The duration between two Covishield doses was increased from 4 weeks to 12 weeks primarily based on data from international trials where after a first dose the immune response was measured until the second dose was given. “In some cases, due to trial related issues, the second dose was given as late as 12 weeks and still the effect of the first dose was pretty much okay,” she added.