MS Society of Canada Grant Supports Trial of Metformin in Young Patients multiplesclerosisnewstoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from multiplesclerosisnewstoday.com Daily Mail and Mail on Sunday newspapers.
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An online auction event supporting the National Multiple Sclerosis Society is is running through Feb. 13 on Facebook.
Organized by The Dyeing Arts group, the fundraising auction features tie dye and handcraft art from several online communities.
The event arose from a partnership between Lighthouse Outdoor Products (LHO) and The Dyeing Arts Project, both founded by Howard Weinstein, a tie dye artist whose wife was diagnosed in 2018 with multiple sclerosis (MS).
In addition to the National MS Society, the REX Foundation will be supported by this initiative. The foundation is a non-profit organization created to support creativity in arts, sciences and education.
The COVID-19 pandemic made social distancing mandatory and required rapid adoption of new technologies to improve patient access to healthcare. Televisits are one type of telemedicine in which clinical visits are conducted remotely using an audio-visual connection between doctors and patients at home.
Researchers in Italy evaluated the use of telemedicine in MS patients during the COVID-19 pandemic outbreak that was declared in February 2020. Patients were recruited in an Italian general hospital between March 9 and May 18, 2020 (Italy’s lockdown period), and completed at least one televisit.
“The overall response of the community to the program was positive, and will be extended as a permanent service,” the researchers wrote, adding that “although some neurological exam modifications or substitutions were utilized, the televisits provided similar information compared with standard visits.”
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A $2.5 million donation from the Simon Family Trust is supporting the creation of a new center of expertise to help in the development of new therapies for multiple sclerosis (MS) and other neurological diseases.
The new center is being launched by researchers from Gladstone Institutes and the University of California San Francisco (UCSF) and is called Gladstone-UCSF Center for Neurovascular Brain Immunology. It will combine basic and clinical research in vascular biology (the study of blood vessels), immunology, and neuroscience to discover new mechanisms that may control disease.
Clinical manifestations of neurological diseases like MS result from a complex network of mechanisms shared between the brain, and the immune and vascular systems. Although these mechanisms overlap, they have been studied separately, which may be hindering the study of potential therapies.
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A novel medication targeting the protein folate receptor-beta (FR-beta) decreased inflammation and brain damage in a rat model of multiple sclerosis (MS).
The findings were published in the
MS is caused by the immune system attacking the nervous system, and one type of immune cell involved in this attack is the macrophage. In animal models of MS, inflammation-driving macrophages express the protein FR-beta, suggesting that this protein may be a viable therapeutic target.
In the new study, researchers from the University of Turku, Purdue University, and Endocyte (now part of Novartis Institutes for BioMedical Research) tested an investigational FR-beta-targeting medication called EC2319 in a rat model of MS.