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Jan 12, 2021
MONDAY, Jan. 11, 2021 (HealthDay News) For patients with markedly asymmetric Parkinson disease, focused ultrasound subthalamotomy on the side opposite their main motor symptoms improves motor features, according to a study published in the Dec. 24 issue of the
New England Journal of Medicine
.
Raúl Martínez-Fernández, M.D., Ph.D., from the University Hospital HM Puerta del Sur in Móstoles, Spain, and colleagues randomly assigned patients with markedly asymmetric Parkinson disease to undergo either focused ultrasound subthalamotomy on the side opposite their main motor signs or a sham procedure. Forty patients were enrolled, and 27 and 13 were assigned to active treatment and sham procedure (control), respectively.
email article
Focused ultrasound in one brain hemisphere improved motor function on the opposite side of the body in people with Parkinson s disease, but led to frequent, persistent adverse events, a small sham-controlled trial showed.
In a select group of patients with markedly asymmetric Parkinson s signs, focused ultrasound subthalamotomy led to a significant improvement in Movement Disorder Society-Unified Parkinson s Disease Rating Scale motor scores (MDS-UPDRS III) at 4 months compared with sham treatment, with a between-group difference of 8.1 points (95% CI 6.0-10.3,
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