How AI Could Upgrade Brain Stimulation Therapies
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Stereotactic Neurosurgery operation, Pasteur 2 Hospital, Nice, France. A patient with Parkinsons disease is being treated with deep brain stimulation by implanting electrodes in brain and modulating cerebral electrical activity. (Photo: BSIP/Universal Images Group, Getty Images)
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The human brain, just like whatever you’re reading this on, uses electricity to function. Neurons are constantly sending and receiving electrical signals. Everyone’s brain works a bit differently, and scientists are now getting closer to establishing how electrical activity is functioning in individual patients’ brains and how to stimulate it to treat neurological and psychiatric disorders. Some sci
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Maryam Shanechi to lead brain research supported by new NIH award
USC Viterbi writers follow a basic script when interviewing faculty about their work. One question we’re always told to ask is “what are the next steps for your research?” We want to end on a positive note that tells the reader what they might expect down the line. When the interview is finished, we pack it all together in a fun and informative story (like this one!) that leaves readers excited about our brave technological future.
Here, I’ll give you an example:
Just two months ago, Maryam Shanechi, the Andrew and Erna Viterbi Early Career Chair in electrical and computer engineering, said this in an article about her groundbreaking work on treating neurological and mental disorders when I asked her what the next steps were:
Angioplasty Gets a Boost from Smart Stents That Heal and Repair Damaged Tissue
April 8, 2021
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Angioplasty, a surgical procedure that opens blocked arteries, often involves placing a metal tube to hold arterial walls open and prevent them from collapsing once the arterial block is surgically removed. However, a bare metal stent (BMS) causes some injury to the walls of the blood vessel walls, which triggers smooth muscle cells to multiply and migrate to the site to repair the injury. This once again narrows the blood vessel a condition called restenosis.
An article published in the journal
Nature Biomedical Engineering, Exosome-eluting stents for vascular healing after ischaemic injury, reports that scientists at North Carolina State University (NCS) have developed smart stents that help reopen blood vessels and regenerate the tissue. These smart stents can heal blood vessels and repair damaged tissues because they are coated with exosomes derived from mesenchymal stem cells
SNP-Chip: CRISPR-Based Transistor Detects Single Point Mutations SNP-Chip enables amplification-free, electronic, detection of point mutations in DNA from patients with Sickle-Cell Disease and ALS
Long before the COVID-19 pandemic shined a spotlight on CRISPR-based diagnostics, Kiana Aran, PhD, was developing the CRISPR-Chip. It was, according to Aran, the first transistor that uses CRISPR to search the genome for potential mutations. In addition, the graphene field-effect transistor (gFET) did not require amplification or sequencing of the nucleic acid.
Now, two years after its introduction, a group headed by Aran, co-founder and CSO at Cardea Bio, and assistant professor at the Keck Graduate Institute of Applied Life Sciences, is introducing an improved CRISPR-based gFET system, named SNP-Chip.
by Tracey Peake April 6, 2021 .
RALEIGH – Researchers from North Carolina State University have developed an exosome-coated stent with a “smart-release” trigger that could both prevent reopened blood vessels from narrowing and deliver regenerative stem cell-derived therapy to blood-starved, or ischemic, tissue.
Angioplasty – a procedure that opens blocked arteries – often involves placing a metal stent to reinforce arterial walls and prevent them from collapsing once the blockage is removed. However, the stent’s placement usually causes some injury to the blood vessel wall, which stimulates smooth muscle cells to proliferate and migrate to the site in an attempt to repair the injury. The result is restenosis: a re-narrowing of the blood vessel previously opened by angioplasty.