Scientists scramble to see why, in rare cases, even the vaccinated can get COVID-19
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Artists, scholars, scientists, and leaders elected to top arts and science body
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The American Academy of Arts & Sciences April 22 announced its 2021 group of new members, with several Indian Americans chosen in various categories among the 252 new additions.
The Academy was established in 1780 by the countryâs founders to provide guidance to a young nation that would face challenges and need expertise and excellence to emerge stronger. While the founders did not anticipate a year with a historic pandemic, overdue racial reckoning, and political strife, the purpose of electing new members is more compelling than ever, according to a press release.
The 2021 election provides an opportunity to recognize extraordinary people who help solve the worldâs most urgent challenges, create meaning through art, and contribute to the common good from every field, discipline, and profession, it noted.
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Under normal, healthy circulatory conditions, the von Willebrand Factor (vWF) keeps to itself. The large and mysterious glycoprotein moves through the blood, balled up tightly, its reaction sites unexposed. But when significant bleeding occurs, it springs into action, initiating the clotting process.
When it works properly, vWF helps stop bleeding and saves lives. However, according to the Centers for Disease Control and Prevention (CDC), about 60,000 to 100,000 Americans die each year from thrombosis, a disorder characterized by too much clotting. Blood clots can trigger a stroke or heart attack.
According to X. Frank Zhang, associate professor in the Department of Bioengineering at Lehigh University, only one drug has been FDA-approved to target vWF and treat thrombosis, or excessive blood clotting disorders, Caplacizumab. It works by binding to vWF and blocking it from binding to platelets. However, no one has understood the specific mechanism behind how it accomplis