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New delivery method promises relief from antipsychotic medication s adverse side effects

Credit: Georgia Kirkos, Mcmaster University HAMILTON, ON, Jan. 15, 2021 A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body. The leap in efficiency means patients with schizophrenia, bipolar disorder and other conditions could see their doses of powerful antipsychotic medications cut by as much as three quarters, which is expected to spare them from sometimes-debilitating side effects while also significantly reducing the frequency of required treatment. The new method delivers medication in a spray that reaches the brain directly through the nose, offering patients greater ease of use and the promise of improved quality of life, including more reliable, effective treatment.

Wits University scientists artificially infect mosquitoes with human malaria to advance treatment

 E-Mail IMAGE: Scientists at the Wits Research Institute for Malaria, with local and global partners, have artificially infected mosquitoes with human malaria and identified a new chemical compound to treat malaria. view more  Credit: Wits University A vector refers to an organism that carries and transmits an infectious disease, as mosquitoes do malaria. Lead compounds are chemical compounds that show promise as treatment for a disease and may lead to the development of a new drug. Antiplasmodial lead compounds are those that counter parasites of the genus Plasmodium, which is the parasite that infects mosquitoes and causes malaria in people.

New U S /U K startup collaboration brings clean energy and climate tech to

 E-Mail BROOKLYN, New York, Tuesday, January 12, 2021 - Beginning in January, the Urban Future Lab at the NYU Tandon School of Engineering will be the U.S. landing pad for Innovate UK s Global Incubator Programme (GIP), which is designed to cultivate and support the launch of innovative cleantech companies with a strong potential to scale internationally to new markets. The program will provide eight U.K.-based businesses with the opportunity to explore the potential of the U.S. market and access to world-class mentors. The cohort will consist of businesses in electric mobility, distributed energy, and technologies focused on reducing greenhouse gas emissions or addressing the effects of global warming.

Exact sciences licenses targeted digital sequencing; adds leadership in precision oncology

Exact Sciences Corp. (Nasdaq: EXAS) today announced that it has acquired a worldwide exclusive license to the proprietary TARDIS technology from the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. This compelling and technically distinct approach will help expand Exact Sciences leadership in precision oncology and offers a differentiated patient-specific solution in minimal residual disease testing.

A highly sensitive technique for measuring the state of a cytoskeleton

 E-Mail IMAGE: Optical blur was artificially added to microscopic images of reticular and bundle cytoskeleton and the difference between the existing and proposed methods was assessed. In the right figure, the higher. view more  Credit: Associate Professor Takumi Higaki A research group from Kumamoto University, Japan has developed a highly sensitive technique to quantitatively evaluate the extent of cytoskeleton bundling from microscopic images. Until now, analysis of cytoskeleton organization was generally made by manually checking microscopic images. The new method uses microscopic image analysis techniques to automatically measure cytoskeleton organization. The researchers expect it to dramatically improve our understanding of various cellular phenomena related to cytoskeleton bundling.

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