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Attack on ivermectin - With insights from The Wall Street Journal
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Combing Through the Science of COVID
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Mystery of Deadly Last Resort Antibiotic Finally Solved After 70 Years
5 MAY 2021
In the eternal arms race between bacteria and antibiotics, deadly superbugs with resistance to humanity s most vital life-saving medicines continue to emerge and evolve.
It s a growing crisis, but thankfully we are not entirely powerless against the scourge of antibiotic resistance.
In medical scenarios where frontline treatments fail to help patients, doctors can turn to so-called drugs of last resort – treatments set aside until the eleventh hour has come, after prioritized therapies haven t worked out.
Drugs of last resort may be held back for a number of reasons, including side effects, cost factors, patient considerations, and more.
Phase 3 trial finds corticosteroid inhaler speeds recovery time in COVID-19 patients
The corticosteroid budesonide shows promise in treating patients with mild COVID-19 infection. Interim analysis of the phase 3 PRINCIPLE clinical trial was posted to the
medRxiv preprint server. Researchers found a 3-day faster recovery of COVID-19 symptoms in people at high risk for severe side effects administered a budesonide inhaler. There was also a 2.1% reduction in hospitalization and death.
Corticosteroids such as dexamethasone have shown to be effective in alleviating the severity of COVID-19 infection. Adding budesonide could give doctors more options in treating patients, especially as it is already readily available in many primary care settings and is in the World Health Organization’s List of Essential Medicines. The medicine is also known to be easier to use for unwell, comorbid, and potentially frail older patients.
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