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Mountain View family hosts lemonade stand to fight childhood cancer

Pavlakis: Vaccinations in Greece are good but we need 80% to reach wall of immunity

Ludwig Cancer Research study reveals how certain immune cells in body cavities help suppress anti-tumor immunity

Ludwig Cancer Research study shows how certain macrophages dampen anti-tumor immunity

 E-Mail IMAGE: Ludwig Memorial Sloan Kettering s investigators Taha Merghoub, Jedd Wolchok and assistant attending physician Andrew Chow. view more  Credit: Ludwig Cancer Research JUNE 10, 2021, NEW YORK - A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system s cancer-killing CD8+ T cells. Reported in the current issue of Cancer Cell and led by Ludwig investigators Taha Merghoub and Jedd Wolchok at Memorial Sloan Kettering (MSK) and Charles Rudin of MSK, the study shows that cavity-resident macrophages express high levels of Tim-4, a receptor for phosphatidylserine (PS), a molecule that they surprisingly found on the surface of highly activated, cytotoxic and proliferative CD8+ T-cells.

DNA test to predict odds of severe COVID-19 draws scrutiny

Science s COVID-19 reporting is supported by the Heising-Simons Foundation For people not yet vaccinated against COVID-19 or still nervous about venturing into crowds, the sales pitch may be alluring: Drool into a tube to provide your DNA and mail it off to see how likely you are to be among the 10% to 15% of people who will end up in the hospital or die from a SARS-CoV-2 infection. That s the promise of a $175 test an Australian company launched last week in the United States. It combines genetic data with someone s age, sex, and preexisting medical conditions to predict their risk of becoming extremely ill from COVID-19. The firm developed its test using data on thousands of COVID-19 patients in the United Kingdom. It may be a forerunner of similar risk tests: An academic team has recently detailed a simpler genetic test to help determine how aggressively some people infected with SARS-CoV-2 should be treated. Yet several genetics experts warn that how a person s genes influenc

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