Combination therapy may reduce influenza-associated morbidity and mortality
A significant proportion of hospitalized patients with influenza develop complications of acute respiratory distress syndrome, driven by virus-induced cytopathic effects as well as exaggerated host immune response. Reporting in
The American Journal of Pathology, published by Elsevier, investigators have found that treatment with an immune receptor blocker in combination with an antiviral agent markedly improves survival of mice infected with lethal influenza and reduces lung pathology in swine-influenza-infected piglets. Their research also provides insights into the optimal timing of treatment to prevent acute lung injury.
Previously, the investigators found that an excessive influx of neutrophils, infection fighting immune cells, and the networks they create to kill pathogens, known as neutrophil extracellular traps (NETs), contribute to acute lung injury in influenza infection. Formation of NETs by act
Edesa Biotech Reaches Enrollment Milestone in COVID Study pittsburghstar.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pittsburghstar.com Daily Mail and Mail on Sunday newspapers.
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SAN DIEGO, March 15, 2021 (GLOBE NEWSWIRE) Adamis Pharmaceuticals Corporation (NASDAQ:ADMP) ( Company ) announced today that in studies conducted at Galveston National Laboratory (GNL), University of Texas Medical Branch (UTMB) at Galveston, hamsters challenged with the virus that causes COVID-19 (SARS-CoV-2), resulted in decreased inflammation in the lungs of animals treated with Tempol compared to controls. This is the first data demonstrating that Tempol, a novel antioxidant, can reduce inflammation in animals given the virus (SARS-CoV-2) that causes COVID-19. The group plans on submitting the publication to a peer review journal.
Dr. Chien-Te Kent Tseng, Professor of the Department of Microbiology and Immunology and Director of GNL s SARS/MERS/COVID-19 Laboratory at UTMB, commented on these results: In our hamster COVID-19 model, pulmonary inflammation with cellular infiltrates and hemorrhage (mild-to-moderate) is triggered by SARS-CoV-2 infection. Treatment with T
Wilkerson got sick in November and has been fighting for his life ever since. Author: Bary Roy Updated: 1:10 PM CDT March 15, 2021
KILLEEN, Texas It has been one year since the first reported case of the coronavirus surfaced in Bell County as the pandemic began to spread around the world. COVID, I ve called it a ghost because we don t know where it is or where it s lurking and it can just sneak up on you, said Angenet Wilkerson as she sat in the living room of her mother s house in Killeen.
Wilkerson said that both her and her husband Ernest became concerned when the virus arrived in Central Texas because of the racial disparity that came with it.
by Kevin Cody
Over the Christmas holidays, Eric Dellenbach, his wife Erika and twin 7-year-olds Jaxson, and Mia contracted COVID-19. The cases were mild, except Eric’s. He went to an emergency room near his home in Seattle But because he didn’t fit the high risk profile, he returned home. He was just 51 and healthy from a lifetime of surfing and snowboarding.
Dellenbach grew up on Duncan Place in Manhattan Beach. He attended Robinson School, Center Middle School and Mira Costa. Upon graduation he attended San Diego State and then met his wife Erika. After a few years he moved his family to the Seattle area for a job in hospital administration.