Lung mechanics and hypoxemia in COVID-19 patients with ARDS
Researchers have created a dataset of COVID-19 patients with acute respiratory distress syndrome to help characterize lung compliance and hypoxemia, which may help administer better treatments.
The severity of COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranges from no symptoms in some patients to severe disease, including death in others. Some patients require mechanical ventilation for respiratory failure and acute respiratory distress syndrome (ARDS). How COVID-19 related ARDS is different from other ARDS is still a subject of debate. Previous studies have small sample sizes and often do not have data on lung mechanics.
Published: Jan 28, 2021
SAN DIEGO, Jan. 28, 2021 (GLOBE NEWSWIRE)
Adamis Pharmaceuticals Corporation (NASDAQ: ADMP) (“Adamis”) in collaboration with the Human Immune Monitoring Center at Stanford University have conducted a study to investigate the effects of Tempol on immune cells from COVID-19 patients. Preliminary data from that study shows that Tempol decreases cytokines from stimulated cells from COVID-19 patients. The collaboration expects to submit the final data to a peer reviewed journal.
Tempol has previously demonstrated both potent anti-inflammatory, anticoagulant, and antioxidant activity. Both inflammatory cytokines and reactive oxygen species (ROS) from cells of the immune system called macrophages and neutrophils damage the lung in Acute Respiratory Distress Syndrome (ARDS). In animal models, Tempol has been shown to decrease proinflammatory cytokines (cytokine storm), and through its potent antioxidant activity has been shown to decrease the harmful ef
Cloe Poisson :: CTMirror.org
Alan Miller, 78, of Marlborough, receives the first dose of the Pfizer vaccine from Valerie Faiella, RN, at Connecticut’s largest drive-through vaccination clinic administered by Community Health Center, Inc. The 10-lane clinic, which opened January 18 at Pratt & Whitney Runway in East Hartford vaccinates eligible individuals in Phase 1a and 1b by appointment only.
The aforementioned article, written by Genevieve Diamant, stands to do potentially significant damage to the efforts by the citizens and government of the State of Connecticut to bring under control the COVID-19 pandemic. The author has made a number of significant errors in data interpretation, and thus the conclusions of the article are not supported by scientific data. It is my belief that the readership of the CT Mirror should be made aware of this fact and of the true facts surrounding the author’s topics of discussion.
Litany of poor medical treatment for Shonisani Lethole at Tembisa hospital Lethole s body remained in hospital bed for 10 hours after death 27 January 2021 - 14:32 Image: #JusticeforShoni/Change.org
Shonisani Lethole s lifeless body spent 10 hours and 15 minutes on the Tembisa Provincial Tertiary Hospital bed until a doctor certified him dead the next day.
Lethole, 34, died on June 29 at 10.30pm, as recorded by a professional nurse.
The doctor on duty was called twice by nursing staff to certify Lethole s death. Dr Babayombe Bangala did not respond.
It turns out Bangala was busy resuscitating another patient in another ward, who ultimately died.
Bangala failed to follow up on the request from his colleagues to assist and knocked off without certifying Lethole dead.
These symptoms range from muscle weakness and fatigue, anxiety and depression, to more severe respiratory issues.
These long-term effects of the virus are what some scientists are calling long-Covid. However, while this study is one of the first large studies on long-Covid, much remains uncertain about the virus’ lasting impact on the body.
“We’re not 100% sure how many people are going to suffer from ongoing symptoms. It’s not the case in all circumstances, but conversely it actually is the case that some patients in the acute illness are relatively asymptomatic, so it’s difficult to know how many people will have ongoing symptoms or in fact how long those symptoms will actually last for,” says Guy Richards, professor emeritus in critical care at Wits University.