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December 11, 2020
Bengaluru company will work with Slovenia-based Educell for trials in Europe
Stempeutics Research Pvt Ltd, a Bengaluru-based company working on stem-cell-based treatment and Slovenia-based Educell Ltd, which focusses on the development of cell therapy products, will tie up for the clinical trials of ‘Stempeucel’ for Covid-19 indications.
Stempeucel has been approved by the Drug Controller General of India (DGCI) for the treatment of CLI due to Buerger’s Disease and Atherosclerotic Peripheral Arterial Disease. Stempeutics is now planning, with Educell, to initiate clinical trials of the drug for Covid-19 related infections in India and Eastern Europe. Stempeutics is part of the Manipal Education and Medical Group, which runs hospitals and medical colleges.
(Tiia Monto/CC BY-SA 3.0)
Israeli biotech Pluristem is canning its experimental phase 3 critical limb ischemia therapy after an outside review said it was no good.
Haifa, Israel-based Pluristem’s R&D operation is built upon placenta-derived adherent stromal cells, which the biotech has designed for use in patients of all human leukocyte antigen types. This approach is made possible by the low immunogenicity of the cells. Once inside the body, Pluristem hopes the cells will drive the healing of injured tissue.
But one of its leading contenders using this approach has been judged a failure in phase 3: An independent data monitoring committee (DMC) took a look at the ongoing data for its pivotal phase 3 in patients with critical limb ischemia (CLI), a severe obstruction of the arteries which markedly reduces blood flow to the extremities and can lead to amputation.
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HOUSTON, Dec. 10, 2020 /PRNewswire/ FibroGenesis, a Texas-based regenerative medicine company focused on tissue regeneration and chronic disease reversal using Human Dermal Fibroblasts (HDFs), today announced the incorporation of Apple Watch to monitor patients through the course of global studies using PneumoBlast™, for the treatment of Acute Respiratory Distress Syndrome (ARDS) in patients affected by COVID-19.
The Apple Watch will be integrated into FibroGenesis Trial Analytics Platform (FibroTap™), a proprietary online platform developed as a follow-up tool for clinical studies, with the goal to track and continuously monitor in real-time, physiological signals from the Apple Watch. The signals will make it possible to identify patients who may be falling ill or developing adverse events and enabling rapid intervention by medical staff.
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