Study suggests that cancer cells may evade chemotherapy by going dormant edexlive.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from edexlive.com Daily Mail and Mail on Sunday newspapers.
Cancer cells may evade chemotherapy by going dormant, suggests study ANI | Updated: Mar 13, 2021 11:24 IST
Washington [US], March 13 (ANI): Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of active hibernation that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study.
The study was led by scientists at Weill Cornell Medicine. These findings have implications for developing new drug combinations that could block senescence and make chemotherapy more effective.
In a study published Jan. 26 in Cancer Discovery, a journal of the American Association for Cancer Research, the investigators reported that this biologic process could help explain why cancers so often recur after treatment. The research was done in both organoids and mouse models made from patients samples of acute myeloid leukaemia (AML) tumours. T
Study finds cancer cells may evade chemotherapy by going dormant eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Gene Responsible For Longer Lifespan Helps Cope-Up Stress by Karishma Abhishek on February 21, 2021 at 11:24 PM Nature Communications. Forkhead box protein O3 (FOXO3) . FOXO3, when exposed to oxidative stress, is involved in triggering programmed cell death (apoptosis) in the absence of survival factors, including neuronal cell death.
Early studies done by the team suggest that lack of FOXO3 gene in the mice brain renders them incapable of coping up with stressful conditions in the brain, which leads to the progressive death of neurons. FOXO3 thus preserves the brain s ability to regenerate by preventing stem cells from dividing until the environment will support the new cells survival.
Study reveals how a longevity gene protects brain stem cells from stress eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.