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IMAGE: Goodluck Lyatuu, doctor and doctoral student at the Department of Global Public Health, Karolinska Institutet. view more
Credit: Karolinska Institutet.
Anti-retroviral drugs are a vital tool in the prevention and treatment of HIV. A new study of pregnant women in Tanzania shows that life-long antiviral treatment also seems to prevent viral transmission from mother to baby. The results of the study, which was conducted in part by researchers at Karolinska Institutet in Sweden and published in
Lancet HIV, make a promising contribution to the WHO s work with HIV prevention in low and middle-income countries.
Just over eight years ago, the World Health Organisation (WHO) issued recommendations known as Option B+ for a simpler and more effective prevention and treatment for HIV during and beyond pregnancy in low and middle-income countries.
Credit: Gabriel Chamie
Universal HIV testing with linkage to treatment and prevention may be a promising approach to accelerate reductions in new infections in generalized epidemic settings, according to a study published February 9th, 2021 in the open-access journal
PLOS Medicine by Catherine Koss of the University of California, San Francisco, and colleagues.
Despite major gains in HIV testing and treatment, in 2019 there were 1.7 million new HIV infections, of which nearly 60% occurred in sub-Saharan Africa. Daily oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate/emtricitabine is highly effective for HIV prevention and could substantially reduce new HIV infections if offered alongside access to HIV testing and treatment. But little is known about the incidence of new HIV infections among PrEP users in settings with generalized HIV epidemics, particularly outside of selected risk groups. To address this knowledge gap, Koss and colleagues conducted communit
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IMAGE: INRS Professor Julien van Grevenynghe, expert in immunology and virology, and doctoral student Hamza Loucif, first author of the paper. view more
Credit: INRS
Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells. The study, led by doctoral student Hamza Loucif and Professor Julien van Grevenynghe, was published in the journal
Autophagy.
Most people infected with HIV-1 require daily antiretroviral therapy to control the infection. These drugs cause significant side effects without fully restoring the normal functioning of the immune system. Yet, a specific group of patients, called elite controllers , are able to live with the infection without any drug intervention.
Joseph Sonnabend, Early Force in Fight Against AIDS, Dies at 88
At the epicenter of the epidemic in New York City, he was a pioneer researcher who, as a clinician, also made house calls.
Dr. Joseph Sonnabend in 2014. As both a physician and a researcher, he was one of the most important figures in the fight against AIDS, if also one of the most unheralded.Credit.Simon Watney
Published Jan. 30, 2021Updated Feb. 1, 2021
When he was growing up in Rhodesia, now Zimbabwe, in the 1930s and ’40s, Joseph Sonnabend would watch his mother, a physician, make house calls in the middle of the night and talk with patients on the phone at all hours. He didn’t want to follow that path, but he did study medicine and become a medical researcher, working alongside Nobel laureates in England on virology and immunology.