The Cougars forced Cincinnati into 13 turnovers, which Houston converted into 22 points.
The margin of victory was the largest for either team in the series, besting a 115-78 win by the Bearcats in Dec. 1998. Cincinnati leads the series with Houston 34-6.
Houston entered 2-2 in its previous four games and fell to Wichita State 68-63 on Thursday.
“All respect to (Cincinnati coach) John (Brannen) and his program, but this game was about us,” Sampson said. “When you play 25, 30, 40 games, you’re going to have games where you just don’t play good. We know that. … Tonight, our intensity level and how hard we play, it was good to see us get back to that level.”
Grimes scores 20, No 6 Houston routs Cincinnati 90-52
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