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Patients with rheumatoid arthritis (RA) who were treated with oral glucocorticoids and proton pump inhibitors (PPIs) were at increased risk for osteoporotic fracture, a large cohort study found.
Patients who were concomitant users of glucocorticoids and PPIs had a 1.6-fold increased risk of osteoporotic fracture (adjusted HR 1.60, 95% CI 1.35-1.89), reported Frank de Vries, PharmD, PhD, of Utrecht University in the Netherlands, and colleagues.
In contrast, for those who used either oral glucocorticoids or PPIs alone, the risk was only 1.2-fold higher. For glucocorticoid use alone, the adjusted hazard ratio was 1.23 (95% CI 1.03-1.47), while for PPI use the hazard ratio was 1.22 (95% CI 1.05-1.42), which were statistically lower than for concomitant use of the two, according to the team s study online in
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It is a well-known rule No. 1 in social media engagement: never read the comments section. Many an unsuspecting academic has innocently posted or been quoted about a controversial topic, and then received a torrent of abuse for their position. I have been abused for my position on vaping (am killing people), a psychiatry colleague who after talking about COVID healthcare worker stress should be grateful she had a Job #$ %, and the list goes on..
MedPage Today as an op-ed. I went to have a look at the comments and apart from some suggestions to use ivermectin and questions about why I was surprised that so many patients died on ventilator, I discovered some great comments including a Charles Dickens quote: It s always something, to know you ve done the most you could. But, don t leave off hoping, or it s of no use doing anything. Hope, hope to the last.
WASHINGTON For Jennie Jacoby, JD, healthcare bias is a two-generation problem in her family. My story started with my mother, who is a Black woman, Jacoby said in a phone interview, adding that her father is white and Jewish. When my mom was pregnant with me 32 years ago, she had access to really great care, but unfortunately due to some implicit bias and medical racism, she had preeclampsia and the doctors completely missed it they assumed she was just an overweight black woman, which is really a dangerous assumption to make; that, on top of doctors being distracted by the fact that my parents were in an interracial marriage, really caused harm to her pregnancy. She almost lost her life and I was born at 3 lbs. 12 oz.
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Now that the first COVID-19 vaccines are being rolled out, Operation Warp Speed, the FDA, and the CDC have recommended that governors proceed first with vaccinating two groups: healthcare workers and residents in nursing homes. But what about after that?
Planning has started in all the states and territories regarding who will get the vaccine third on the priority list, potentially starting before the end of January. The choice can be reduced to two major categories: maintenance of essential services and reduction of hospitalizations and mortality.
Operation Warp Speed, FDA, and CDC have recommended that priority should go to workers who preserve essential services for the COVID-19 response and for the overall functioning of society. Estimated at 87 million, this category includes food and medicine supply chain workers (e.g., truck drivers, grocery store and pharmacy employees), infrastructure workers, teachers, and those working in national security. The essen