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Cat Models Hold Potential To Treat Chronic Kidney Disease

Cat Models Hold Potential To Treat Chronic Kidney Disease by Karishma Abhishek on  March 14, 2021 at 7:08 AM The Wake Forest Institute for Regenerative Medicine (WFIRM), a study published online by Frontiers in Veterinary Science in the Veterinary Regenerative Medicine platform. Chronic kidney disease is a condition affecting 37 million people in the US (as per Centers for Disease Control), in which the kidneys are damaged and cannot filter blood as normal. This may progress to end-stage kidney failure, which is fatal without dialysis or a kidney transplant. About 58 million cats in the United States are estimated to suffer from chronic kidney disease thereby affecting 30-50% of cats age 15 years or older, according to the

You are not a cat, but a cat could someday help treat your chronic kidney disease

 E-Mail WINSTON-SALEM, NC - March 12, 2021 - The Wake Forest Institute for Regenerative Medicine is investigating how cats with chronic kidney disease could someday help inform treatment for humans. In humans, treatment for chronic kidney disease a condition in which the kidneys are damaged and cannot filter blood as well as they should focuses on slowing the progression of the organ damage. The condition can progress to end-stage kidney failure, which is fatal without dialysis or a kidney transplant. An estimated 37 million people in the US suffer from chronic kidney disease, according to the Centers for Disease Control. The American Veterinary Medical Association estimates there are about 58 million cats in the United States. Chronic kidney disease affects 30-50% of cats age 15 years or older. The fibrosis or scarring that occurs as a result of the disease is a common final pathway for kidney disease in both animals and people. For cats, end-stage kidney disease has no effe

Bone marrow cell injections may lead to reduction in brain injury after stroke

Bone marrow cell injections may lead to reduction in brain injury after stroke Results of a clinical trial released in STEM CELLS Translational Medicine provide evidence that treating patients with an injection of bone marrow cells may lead to a reduction in brain injury after a stroke. The study was conducted by Muhammad E. Haque, Ph.D., Sean I. Savitz, M.D., and colleagues from the Institute for Stroke and Cerebrovascular Disease at The University of Texas Health Science Center in Houston. Nearly 90 percent of patients who suffer an ischemic stroke - the most common type of stroke - exhibit weakness or paralysis to one side of the body. Injuries to the corticospinal tract (CST), which is the main white matter connection in the brain responsible for carrying movement-related information to the spinal cord, is the primary cause of this motor function impairment. In stroke animal models, we ve seen how bone marrow mononuclear cells (BM-MNC) attenuate secondary degeneration and en

Study provides evidence that bone marrow cell injections help heal the brain after stroke

 E-Mail IMAGE: Autologous bone-marrow mononuclear cells were intravenously administered in patients with acute ischemic stroke as procedure outline in panel A. The non-treated patients were recruited separately. Both groups were imaged. view more  Credit: AlphaMed Press Durham, NC - Results of a clinical trial released in STEM CELLS Translational Medicine provide evidence that treating patients with an injection of bone marrow cells may lead to a reduction in brain injury after a stroke. The study was conducted by Muhammad E. Haque, Ph.D., Sean I. Savitz, M.D., and colleagues from the Institute for Stroke and Cerebrovascular Disease at The University of Texas Health Science Center in Houston. Nearly 90 percent of patients who suffer an ischemic stroke - the most common type of stroke - exhibit weakness or paralysis to one side of the body, Dr. Haque said. Injuries to the corticospinal tract (CST), which is the main white matter connection in the brain responsibl

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